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ZW10 (zw10 kinetochore protein)

Identity

Alias_namesZW10 (Drosophila) homolog, centromere/kinetochore protein
ZW10, kinetochore associated, homolog (Drosophila)
Alias_symbol (synonym)KNTC1AP
Other aliasHZW10
HGNC (Hugo) ZW10
LocusID (NCBI) 9183
Atlas_Id 42887
Location 11q23.2  [Link to chromosome band 11q23]
Location_base_pair Starts at 113733183 and ends at 113773763 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZW10   13194
Cards
Entrez_Gene (NCBI)ZW10  9183  zw10 kinetochore protein
AliasesHZW10; KNTC1AP
GeneCards (Weizmann)ZW10
Ensembl hg19 (Hinxton)ENSG00000086827 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000086827 [Gene_View]  chr11:113733183-113773763 [Contig_View]  ZW10 [Vega]
ICGC DataPortalENSG00000086827
TCGA cBioPortalZW10
AceView (NCBI)ZW10
Genatlas (Paris)ZW10
WikiGenes9183
SOURCE (Princeton)ZW10
Genetics Home Reference (NIH)ZW10
Genomic and cartography
GoldenPath hg38 (UCSC)ZW10  -     chr11:113733183-113773763 -  11q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZW10  -     11q23.2   [Description]    (hg19-Feb_2009)
EnsemblZW10 - 11q23.2 [CytoView hg19]  ZW10 - 11q23.2 [CytoView hg38]
Mapping of homologs : NCBIZW10 [Mapview hg19]  ZW10 [Mapview hg38]
OMIM603954   
Gene and transcription
Genbank (Entrez)AK300746 AK303871 AK312925 BC128264 BI547129
RefSeq transcript (Entrez)NM_004724
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZW10
Cluster EST : UnigeneHs.503886 [ NCBI ]
CGAP (NCI)Hs.503886
Alternative Splicing GalleryENSG00000086827
Gene ExpressionZW10 [ NCBI-GEO ]   ZW10 [ EBI - ARRAY_EXPRESS ]   ZW10 [ SEEK ]   ZW10 [ MEM ]
Gene Expression Viewer (FireBrowse)ZW10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9183
GTEX Portal (Tissue expression)ZW10
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43264   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43264  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43264
Splice isoforms : SwissVarO43264
PhosPhoSitePlusO43264
Domains : Interpro (EBI)RZZ-complex_Zw10   
Domain families : Pfam (Sanger)Zw10 (PF06248)   
Domain families : Pfam (NCBI)pfam06248   
Conserved Domain (NCBI)ZW10
DMDM Disease mutations9183
Blocks (Seattle)ZW10
SuperfamilyO43264
Human Protein AtlasENSG00000086827
Peptide AtlasO43264
HPRD04902
IPIIPI00011631   IPI01015739   IPI01014384   
Protein Interaction databases
DIP (DOE-UCLA)O43264
IntAct (EBI)O43264
FunCoupENSG00000086827
BioGRIDZW10
STRING (EMBL)ZW10
ZODIACZW10
Ontologies - Pathways
QuickGOO43264
Ontology : AmiGOmitotic sister chromatid segregation  establishment of mitotic spindle orientation  kinetochore  condensed chromosome kinetochore  spindle pole  protein binding  nucleus  endoplasmic reticulum  endoplasmic reticulum membrane  kinetochore microtubule  cytosol  cytosol  protein complex assembly  ER to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to ER  Golgi organization  Golgi organization  sister chromatid cohesion  mitotic metaphase plate congression  mitotic cell cycle checkpoint  mitotic spindle assembly checkpoint  regulation of exit from mitosis  protein transport  membrane  centromeric DNA binding  protein localization to kinetochore  cell division  meiotic cell cycle  Dsl1/NZR complex  RZZ complex  
Ontology : EGO-EBImitotic sister chromatid segregation  establishment of mitotic spindle orientation  kinetochore  condensed chromosome kinetochore  spindle pole  protein binding  nucleus  endoplasmic reticulum  endoplasmic reticulum membrane  kinetochore microtubule  cytosol  cytosol  protein complex assembly  ER to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to ER  Golgi organization  Golgi organization  sister chromatid cohesion  mitotic metaphase plate congression  mitotic cell cycle checkpoint  mitotic spindle assembly checkpoint  regulation of exit from mitosis  protein transport  membrane  centromeric DNA binding  protein localization to kinetochore  cell division  meiotic cell cycle  Dsl1/NZR complex  RZZ complex  
NDEx NetworkZW10
Atlas of Cancer Signalling NetworkZW10
Wikipedia pathwaysZW10
Orthology - Evolution
OrthoDB9183
GeneTree (enSembl)ENSG00000086827
Phylogenetic Trees/Animal Genes : TreeFamZW10
HOVERGENO43264
HOGENOMO43264
Homologs : HomoloGeneZW10
Homology/Alignments : Family Browser (UCSC)ZW10
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZW10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZW10
dbVarZW10
ClinVarZW10
1000_GenomesZW10 
Exome Variant ServerZW10
ExAC (Exome Aggregation Consortium)ZW10 (select the gene name)
Genetic variants : HAPMAP9183
Genomic Variants (DGV)ZW10 [DGVbeta]
DECIPHERZW10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZW10 
Mutations
ICGC Data PortalZW10 
TCGA Data PortalZW10 
Broad Tumor PortalZW10
OASIS PortalZW10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZW10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZW10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZW10
DgiDB (Drug Gene Interaction Database)ZW10
DoCM (Curated mutations)ZW10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZW10 (select a term)
intoGenZW10
Cancer3DZW10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603954   
Orphanet
MedgenZW10
Genetic Testing Registry ZW10
NextProtO43264 [Medical]
TSGene9183
GENETestsZW10
Target ValidationZW10
Huge Navigator ZW10 [HugePedia]
snp3D : Map Gene to Disease9183
BioCentury BCIQZW10
ClinGenZW10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9183
Chemical/Pharm GKB GenePA37759
Clinical trialZW10
Miscellaneous
canSAR (ICR)ZW10 (select the gene name)
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZW10
EVEXZW10
GoPubMedZW10
iHOPZW10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 13:04:03 CEST 2017

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