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ZW10 (zw10 kinetochore protein)

Identity

Alias (NCBI)HZW10
KNTC1AP
HGNC (Hugo) ZW10
HGNC Alias symbKNTC1AP
HGNC Previous nameZW10 (Drosophila) homolog, centromere/kinetochore protein
 ZW10, kinetochore associated, homolog (Drosophila)
LocusID (NCBI) 9183
Atlas_Id 42887
Location 11q23.2  [Link to chromosome band 11q23]
Location_base_pair Starts at 113733187 and ends at 113773692 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)ZW10   13194
Cards
Entrez_Gene (NCBI)ZW10    zw10 kinetochore protein
AliasesHZW10; KNTC1AP
GeneCards (Weizmann)ZW10
Ensembl hg19 (Hinxton)ENSG00000086827 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000086827 [Gene_View]  ENSG00000086827 [Sequence]  chr11:113733187-113773692 [Contig_View]  ZW10 [Vega]
ICGC DataPortalENSG00000086827
TCGA cBioPortalZW10
AceView (NCBI)ZW10
Genatlas (Paris)ZW10
SOURCE (Princeton)ZW10
Genetics Home Reference (NIH)ZW10
Genomic and cartography
GoldenPath hg38 (UCSC)ZW10  -     chr11:113733187-113773692 -  11q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZW10  -     11q23.2   [Description]    (hg19-Feb_2009)
GoldenPathZW10 - 11q23.2 [CytoView hg19]  ZW10 - 11q23.2 [CytoView hg38]
ImmunoBaseENSG00000086827
genome Data Viewer NCBIZW10 [Mapview hg19]  
OMIM603954   
Gene and transcription
Genbank (Entrez)AK300746 AK303871 AK312925 BC128264 BI547129
RefSeq transcript (Entrez)NM_004724
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZW10
Alternative Splicing GalleryENSG00000086827
Gene ExpressionZW10 [ NCBI-GEO ]   ZW10 [ EBI - ARRAY_EXPRESS ]   ZW10 [ SEEK ]   ZW10 [ MEM ]
Gene Expression Viewer (FireBrowse)ZW10 [ Firebrowse - Broad ]
GenevisibleExpression of ZW10 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9183
GTEX Portal (Tissue expression)ZW10
Human Protein AtlasENSG00000086827-ZW10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43264   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43264  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43264
Splice isoforms : SwissVarO43264
PhosPhoSitePlusO43264
Domains : Interpro (EBI)RZZ-complex_Zw10   
Domain families : Pfam (Sanger)Zw10 (PF06248)   
Domain families : Pfam (NCBI)pfam06248   
Conserved Domain (NCBI)ZW10
Blocks (Seattle)ZW10
SuperfamilyO43264
Human Protein Atlas [tissue]ENSG00000086827-ZW10 [tissue]
Peptide AtlasO43264
HPRD04902
IPIIPI00011631   IPI01015739   IPI01014384   
Protein Interaction databases
DIP (DOE-UCLA)O43264
IntAct (EBI)O43264
BioGRIDZW10
STRING (EMBL)ZW10
ZODIACZW10
Ontologies - Pathways
QuickGOO43264
Ontology : AmiGOmitotic sister chromatid segregation  establishment of mitotic spindle orientation  kinetochore  condensed chromosome kinetochore  spindle pole  protein binding  nucleus  endoplasmic reticulum  endoplasmic reticulum membrane  lipid droplet  kinetochore microtubule  cytosol  cytosol  ER to Golgi vesicle-mediated transport  ER to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to ER  Golgi organization  Golgi organization  mitotic metaphase plate congression  mitotic cell cycle checkpoint  mitotic spindle assembly checkpoint  regulation of exit from mitosis  protein transport  membrane  centromeric DNA binding  protein localization to kinetochore  cell division  meiotic cell cycle  protein-containing complex assembly  Dsl1/NZR complex  RZZ complex  RZZ complex  
Ontology : EGO-EBImitotic sister chromatid segregation  establishment of mitotic spindle orientation  kinetochore  condensed chromosome kinetochore  spindle pole  protein binding  nucleus  endoplasmic reticulum  endoplasmic reticulum membrane  lipid droplet  kinetochore microtubule  cytosol  cytosol  ER to Golgi vesicle-mediated transport  ER to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to ER  Golgi organization  Golgi organization  mitotic metaphase plate congression  mitotic cell cycle checkpoint  mitotic spindle assembly checkpoint  regulation of exit from mitosis  protein transport  membrane  centromeric DNA binding  protein localization to kinetochore  cell division  meiotic cell cycle  protein-containing complex assembly  Dsl1/NZR complex  RZZ complex  RZZ complex  
NDEx NetworkZW10
Atlas of Cancer Signalling NetworkZW10
Wikipedia pathwaysZW10
Orthology - Evolution
OrthoDB9183
GeneTree (enSembl)ENSG00000086827
Phylogenetic Trees/Animal Genes : TreeFamZW10
HOGENOMO43264
Homologs : HomoloGeneZW10
Homology/Alignments : Family Browser (UCSC)ZW10
Gene fusions - Rearrangements
Fusion : QuiverZW10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZW10 [hg38]
dbVarZW10
ClinVarZW10
MonarchZW10
1000_GenomesZW10 
Exome Variant ServerZW10
GNOMAD BrowserENSG00000086827
Varsome BrowserZW10
Genomic Variants (DGV)ZW10 [DGVbeta]
DECIPHERZW10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZW10 
Mutations
ICGC Data PortalZW10 
TCGA Data PortalZW10 
Broad Tumor PortalZW10
OASIS PortalZW10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZW10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZW10
Mutations and Diseases : HGMDZW10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZW10
DgiDB (Drug Gene Interaction Database)ZW10
DoCM (Curated mutations)ZW10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZW10 (select a term)
intoGenZW10
Cancer3DZW10(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603954   
Orphanet
DisGeNETZW10
MedgenZW10
Genetic Testing Registry ZW10
NextProtO43264 [Medical]
GENETestsZW10
Target ValidationZW10
Huge Navigator ZW10 [HugePedia]
ClinGenZW10
Clinical trials, drugs, therapy
MyCancerGenomeZW10
Protein Interactions : CTD
Pharm GKB GenePA37759
PharosO43264
Clinical trialZW10
Miscellaneous
canSAR (ICR)ZW10 (select the gene name)
HarmonizomeZW10
DataMed IndexZW10
Probes
Litterature
PubMed64 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZW10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jan 1 18:45:37 CET 2021

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