ZYG11A (zyg-11 family member A, cell cycle regulator)

2017-01-01  

Identity

HGNC
LOCATION
1p32.3
LOCUSID
ALIAS
ZYG11

Other Information

Locus ID:

NCBI: 440590
MIM: 618675
HGNC: 32058
Ensembl: ENSG00000203995

Variants:

dbSNP: 440590
ClinVar: 440590
TCGA: ENSG00000203995
COSMIC: ZYG11A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000203995ENST00000371528Q6WRX3
ENSG00000203995ENST00000371532Q6WRX3
ENSG00000203995ENST00000612017Q6WRX3

Expression (GTEx)

0
1
2
3
4
5
6
7

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
267712372016ZYG11A serves as an oncogene in non-small cell lung cancer and influences CCNE1 expression.14
278109092016The ubiquitin ligase CRL2ZYG11 targets cyclin B1 for degradation in a conserved pathway that facilitates mitotic slippage.10

Citation

Dessen P

ZYG11A (zyg-11 family member A, cell cycle regulator)

Atlas Genet Cytogenet Oncol Haematol. 2017-01-01

Online version: http://atlasgeneticsoncology.org/gene/56702/zyg11a