Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZYX (zyxin)

Identity

Other aliasESP-2
HED-2
HGNC (Hugo) ZYX
LocusID (NCBI) 7791
Atlas_Id 45507
Location 7q34  [Link to chromosome band 7q34]
Location_base_pair Starts at 143381267 and ends at 143391111 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
C7orf50 (7p22.3) / ZYX (7q34)MAN1A2 (1p12) / ZYX (7q34)TGFBI (5q31.1) / ZYX (7q34)
UBAP1L (15q22.31) / ZYX (7q34)WBSCR22 (7q11.23) / ZYX (7q34)ZYX (7q34) / NCAPH (2q11.2)
ZYX (7q34) / NUDCD3 (7p13)ZYX (7q34) / WBSCR22 (7q11.23)ZYX (7q34) / ZYX (7q34)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZYX   13200
Cards
Entrez_Gene (NCBI)ZYX  7791  zyxin
AliasesESP-2; HED-2
GeneCards (Weizmann)ZYX
Ensembl hg19 (Hinxton)ENSG00000159840 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000159840 [Gene_View]  chr7:143381267-143391111 [Contig_View]  ZYX [Vega]
ICGC DataPortalENSG00000159840
TCGA cBioPortalZYX
AceView (NCBI)ZYX
Genatlas (Paris)ZYX
WikiGenes7791
SOURCE (Princeton)ZYX
Genetics Home Reference (NIH)ZYX
Genomic and cartography
GoldenPath hg38 (UCSC)ZYX  -     chr7:143381267-143391111 +  7q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZYX  -     7q34   [Description]    (hg19-Feb_2009)
EnsemblZYX - 7q34 [CytoView hg19]  ZYX - 7q34 [CytoView hg38]
Mapping of homologs : NCBIZYX [Mapview hg19]  ZYX [Mapview hg38]
OMIM602002   
Gene and transcription
Genbank (Entrez)AK130138 AK298925 AK299005 AK302309 AK316227
RefSeq transcript (Entrez)NM_001010972 NM_003461
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZYX
Cluster EST : UnigeneHs.490415 [ NCBI ]
CGAP (NCI)Hs.490415
Alternative Splicing GalleryENSG00000159840
Gene ExpressionZYX [ NCBI-GEO ]   ZYX [ EBI - ARRAY_EXPRESS ]   ZYX [ SEEK ]   ZYX [ MEM ]
Gene Expression Viewer (FireBrowse)ZYX [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7791
GTEX Portal (Tissue expression)ZYX
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15942   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15942  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15942
Splice isoforms : SwissVarQ15942
PhosPhoSitePlusQ15942
Domaine pattern : Prosite (Expaxy)LIM_DOMAIN_1 (PS00478)    LIM_DOMAIN_2 (PS50023)   
Domains : Interpro (EBI)Znf_LIM   
Domain families : Pfam (Sanger)LIM (PF00412)   
Domain families : Pfam (NCBI)pfam00412   
Domain families : Smart (EMBL)LIM (SM00132)  
Conserved Domain (NCBI)ZYX
DMDM Disease mutations7791
Blocks (Seattle)ZYX
SuperfamilyQ15942
Human Protein AtlasENSG00000159840
Peptide AtlasQ15942
HPRD03592
IPIIPI00926625   IPI00871311   IPI00941977   IPI00658086   IPI00925876   IPI00926316   IPI00926534   IPI00924931   
Protein Interaction databases
DIP (DOE-UCLA)Q15942
IntAct (EBI)Q15942
FunCoupENSG00000159840
BioGRIDZYX
STRING (EMBL)ZYX
ZODIACZYX
Ontologies - Pathways
QuickGOQ15942
Ontology : AmiGOstress fiber  RNA binding  protein binding  nucleus  cytosol  plasma membrane  integral component of plasma membrane  cell-cell adherens junction  focal adhesion  cell adhesion  cell-matrix adhesion  signal transduction  transforming growth factor beta receptor signaling pathway  integrin-mediated signaling pathway  cell-cell signaling  zinc ion binding  viral process  stress fiber assembly  regulation of inflammatory response  
Ontology : EGO-EBIstress fiber  RNA binding  protein binding  nucleus  cytosol  plasma membrane  integral component of plasma membrane  cell-cell adherens junction  focal adhesion  cell adhesion  cell-matrix adhesion  signal transduction  transforming growth factor beta receptor signaling pathway  integrin-mediated signaling pathway  cell-cell signaling  zinc ion binding  viral process  stress fiber assembly  regulation of inflammatory response  
Pathways : BIOCARTAIntegrin Signaling Pathway [Genes]   
Pathways : KEGGFocal adhesion   
NDEx NetworkZYX
Atlas of Cancer Signalling NetworkZYX
Wikipedia pathwaysZYX
Orthology - Evolution
OrthoDB7791
GeneTree (enSembl)ENSG00000159840
Phylogenetic Trees/Animal Genes : TreeFamZYX
HOVERGENQ15942
HOGENOMQ15942
Homologs : HomoloGeneZYX
Homology/Alignments : Family Browser (UCSC)ZYX
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZYX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZYX
dbVarZYX
ClinVarZYX
1000_GenomesZYX 
Exome Variant ServerZYX
ExAC (Exome Aggregation Consortium)ZYX (select the gene name)
Genetic variants : HAPMAP7791
Genomic Variants (DGV)ZYX [DGVbeta]
DECIPHERZYX [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZYX 
Mutations
ICGC Data PortalZYX 
TCGA Data PortalZYX 
Broad Tumor PortalZYX
OASIS PortalZYX [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZYX  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZYX
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZYX
DgiDB (Drug Gene Interaction Database)ZYX
DoCM (Curated mutations)ZYX (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZYX (select a term)
intoGenZYX
Cancer3DZYX(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602002   
Orphanet
MedgenZYX
Genetic Testing Registry ZYX
NextProtQ15942 [Medical]
TSGene7791
GENETestsZYX
Target ValidationZYX
Huge Navigator ZYX [HugePedia]
snp3D : Map Gene to Disease7791
BioCentury BCIQZYX
ClinGenZYX
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7791
Chemical/Pharm GKB GenePA37765
Clinical trialZYX
Miscellaneous
canSAR (ICR)ZYX (select the gene name)
Probes
Litterature
PubMed88 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZYX
EVEXZYX
GoPubMedZYX
iHOPZYX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 13:04:03 CEST 2017

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