Expression of granzyme A in salivary gland biopsies from patients with primary Sjogren's syndrome. |
Alpert S, Kang HI, Weissman I, Fox RI. |
Arthritis Rheum. 1994 Jul;37(7):1046-54. |
PMID 8024614 |
|
The molecular basis for perforin oligomerization and transmembrane pore assembly. |
Baran K, Dunstone M, Chia J, Ciccone A, Browne KA, Clarke CJ, Lukoyanova N, Saibil H, Whisstock JC, Voskoboinik I, Trapani JA. |
Immunity. 2009 May;30(5):684-95. Epub 2009 May 14. |
PMID 19446473 |
|
The oligomeric structure of human granzyme A is a determinant of its extended substrate specificity. |
Bell JK, Goetz DH, Mahrus S, Harris JL, Fletterick RJ, Craik CS. |
Nat Struct Biol. 2003 Jul;10(7):527-34. |
PMID 12819769 |
|
Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation. |
Beresford PJ, Xia Z, Greenberg AH, Lieberman J. |
Immunity. 1999 May;10(5):585-94. |
PMID 10367904 |
|
Extracellular granzymes: current perspectives. |
Buzza MS, Bird PI. |
Biol Chem. 2006 Jul;387(7):827-37. (REVIEW) |
PMID 16913832 |
|
Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance. |
Cao X, Cai SF, Fehniger TA, Song J, Collins LI, Piwnica-Worms DR, Ley TJ. |
Immunity. 2007 Oct;27(4):635-46. Epub 2007 Oct 4. |
PMID 17919943 |
|
Granule-associated serine proteases: granzymes might not just be killer proteases. |
Froelich CJ, Pardo J, Simon MM. |
Trends Immunol. 2009 Mar;30(3):117-23. Epub 2009 Feb 13. (REVIEW) |
|
Perforin and granzyme A expression identifying cytolytic lymphocytes in rheumatoid arthritis. |
Griffiths GM, Alpert S, Lambert E, McGuire J, Weissman IL. |
Proc Natl Acad Sci U S A. 1992 Jan 15;89(2):549-53. |
PMID 1731326 |
|
The orphan granzymes of humans and mice. |
Grossman WJ, Revell PA, Lu ZH, Johnson H, Bredemeyer AJ, Ley TJ. |
Curr Opin Immunol. 2003 Oct;15(5):544-52. |
PMID 14499263 |
|
Induction of target cell DNA release by the cytotoxic T lymphocyte granule protease granzyme A. |
Hayes MP, Berrebi GA, Henkart PA. |
J Exp Med. 1989 Sep 1;170(3):933-46. |
PMID 2788710 |
|
Granzymes in age-related cardiovascular and pulmonary diseases. |
Hendel A, Hiebert PR, Boivin WA, Williams SJ, Granville DJ. |
Cell Death Differ. 2010 Apr;17(4):596-606. Epub 2010 Feb 5. (REVIEW) |
PMID 20139894 |
|
Crystal structure of the apoptosis-inducing human granzyme A dimer. |
Hink-Schauer C, Estebanez-Perpina E, Kurschus FC, Bode W, Jenne DE. |
Nat Struct Biol. 2003 Jul;10(7):535-40. |
PMID 12819770 |
|
Granzymes, a family of serine proteases released from granules of cytolytic T lymphocytes upon T cell receptor stimulation. |
Jenne DE, Tschopp J. |
Immunol Rev. 1988 Mar;103:53-71. (REVIEW) |
PMID 3292396 |
|
Are Proteinases Functional Molecules of T Lymphocytes? |
Kramer MD, Simon MM |
Immunol Today. 1987;8:140-2. (REVIEW) |
|
Expression of granzymes A and B in synovial tissue from patients with rheumatoid arthritis and osteoarthritis. |
Kummer JA, Tak PP, Brinkman BM, van Tilborg AA, Kamp AM, Verweij CL, Daha MR, Meinders AE, Hack CE, Breedveld FC. |
Clin Immunol Immunopathol. 1994 Oct;73(1):88-95. |
PMID 7923921 |
|
Granzyme A activates another way to die. |
Lieberman J. |
Immunol Rev. 2010 May;235(1):93-104. (REVIEW) |
PMID 20536557 |
|
Identification of granzyme A isolated from cytotoxic T-lymphocyte-granules as one of the proteases encoded by CTL-specific genes. |
Masson D, Zamai M, Tschopp J. |
FEBS Lett. 1986 Nov 10;208(1):84-8. |
PMID 3533635 |
|
Human and mouse granzyme A induce a proinflammatory cytokine response. |
Metkar SS, Menaa C, Pardo J, Wang B, Wallich R, Freudenberg M, Kim S, Raja SM, Shi L, Simon MM, Froelich CJ. |
Immunity. 2008 Nov 14;29(5):720-33. Epub 2008 Oct 23. |
PMID 18951048 |
|
Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia. |
Mullbacher A, Ebnet K, Blanden RV, Hla RT, Stehle T, Museteanu C, Simon MM. |
Proc Natl Acad Sci U S A. 1996 Jun 11;93(12):5783-7. |
PMID 8650169 |
|
Demonstration of granzyme A and perforin messenger RNA in the synovium of patients with rheumatoid arthritis. |
Muller-Ladner U, Kriegsmann J, Tschopp J, Gay RE, Gay S. |
Arthritis Rheum. 1995 Apr;38(4):477-84. |
PMID 7536415 |
|
Granzyme A-immunoreactive cells in synovial fluid in reactive and rheumatoid arthritis. |
Nordstrom DC, Konttinen YT, Sorsa T, Nykanen P, Pettersson T, Santavirta S, Tschopp J. |
Clin Rheumatol. 1992 Dec;11(4):529-32. |
PMID 1283120 |
|
Granzymes are essential for natural killer cell-mediated and perf-facilitated tumor control. |
Pardo J, Balkow S, Anel A, Simon MM. |
Eur J Immunol. 2002 Oct;32(10):2881-7. |
PMID 12355441 |
|
Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis. |
Pardo J, Bosque A, Brehm R, Wallich R, Naval J, Mullbacher A, Anel A, Simon MM. |
J Cell Biol. 2004 Nov 8;167(3):457-68. |
PMID 15534000 |
|
Granzyme A, a noncytolytic component of CD8(+) cell granules, restricts the spread of herpes simplex virus in the peripheral nervous systems of experimentally infected mice. |
Pereira RA, Simon MM, Simmons A. |
J Virol. 2000 Jan;74(2):1029-32. |
PMID 10623769 |
|
Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo. |
Pham CT, Ley TJ. |
Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8627-32. |
PMID 10411926 |
|
Human perforin employs different avenues to damage membranes. |
Praper T, Sonnen A, Viero G, Kladnik A, Froelich CJ, Anderluh G, Dalla Serra M, Gilbert RJ. |
J Biol Chem. 2011 Jan 28;286(4):2946-55. Epub 2010 Oct 2. |
PMID 20889983 |
|
Nonspecific cytotoxic cells of teleosts are armed with multiple granzymes and other components of the granule exocytosis pathway. |
Praveen K, Leary JH 3rd, Evans DL, Jaso-Friedmann L. |
Mol Immunol. 2006 Mar;43(8):1152-62. Epub 2005 Aug 30. |
PMID 16137766 |
|
Murine cytomegalovirus replication in salivary glands is controlled by both perforin and granzymes during acute infection. |
Riera L, Gariglio M, Valente G, Mullbacher A, Museteanu C, Landolfo S, Simon MM. |
Eur J Immunol. 2000 May;30(5):1350-5. |
PMID 10820381 |
|
Glucocorticoid-induced alternative promoter usage for a novel 5' variant of granzyme A. |
Ruike Y, Katsuma S, Hirasawa A, Tsujimoto G. |
J Hum Genet. 2007;52(2):172-8. Epub 2006 Dec 19. |
PMID 17180578 |
|
A natural killer cell granule protein that induces DNA fragmentation and apoptosis. |
Shi L, Kraut RP, Aebersold R, Greenberg AH. |
J Exp Med. 1992 Feb 1;175(2):553-66. |
PMID 1732416 |
|
Granzyme A initiates an alternative pathway for granule-mediated apoptosis. |
Shresta S, Graubert TA, Thomas DA, Raptis SZ, Ley TJ. |
Immunity. 1999 May;10(5):595-605. |
PMID 10367905 |
|
Purification and characterization of a T cell specific serine proteinase (TSP-1) from cloned cytolytic T lymphocytes. |
Simon MM, Hoschutzky H, Fruth U, Simon HG, Kramer MD. |
EMBO J. 1986 Dec 1;5(12):3267-74. |
PMID 3545816 |
|
Extracellular activities of human granzymes. I. Granzyme A induces IL6 and IL8 production in fibroblast and epithelial cell lines. |
Sower LE, Klimpel GR, Hanna W, Froelich CJ. |
Cell Immunol. 1996 Jul 10;171(1):159-63. |
PMID 8754861 |
|
Extracellular granzymes A and B in humans: detection of native species during CTL responses in vitro and in vivo. |
Spaeny-Dekking EH, Hanna WL, Wolbink AM, Wever PC, Kummer JA, Swaak AJ, Middeldorp JM, Huisman HG, Froelich CJ, Hack CE. |
J Immunol. 1998 Apr 1;160(7):3610-6. |
PMID 9531325 |
|
Granzyme-positive cytotoxic cells are specifically increased in early rheumatoid synovial tissue. |
Tak PP, Kummer JA, Hack CE, Daha MR, Smeets TJ, Erkelens GW, Meinders AE, Kluin PM, Breedveld FC. |
Arthritis Rheum. 1994 Dec;37(12):1735-43. |
PMID 7986219 |
|
The levels of soluble granzyme A and B are elevated in plasma and synovial fluid of patients with rheumatoid arthritis (RA). |
Tak PP, Spaeny-Dekking L, Kraan MC, Breedveld FC, Froelich CJ, Hack CE. |
Clin Exp Immunol. 1999 May;116(2):366-70. |
PMID 10337032 |
|
Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells. |
Thiery J, Keefe D, Boulant S, Boucrot E, Walch M, Martinvalet D, Goping IS, Bleackley RC, Kirchhausen T, Lieberman J. |
Nat Immunol. 2011 Jun 19;12(8):770-7. doi: 10.1038/ni.2050. |
PMID 21685908 |
|
Granzyme activity in the inflamed lung is not controlled by endogenous serine proteinase inhibitors. |
Tremblay GM, Wolbink AM, Cormier Y, Hack CE. |
J Immunol. 2000 Oct 1;165(7):3966-9. |
PMID 11034405 |
|
Increased granzyme A expression in type II pneumocytes of patients with severe chronic obstructive pulmonary disease. |
Vernooy JH, Moller GM, van Suylen RJ, van Spijk MP, Cloots RH, Hoet PH, Pennings HJ, Wouters EF. |
Am J Respir Crit Care Med. 2007 Mar 1;175(5):464-72. Epub 2006 Nov 30. |
PMID 17138956 |
|
Granzyme-like sequences in bony fish shed light on the emergence of hematopoietic serine proteases during vertebrate evolution. |
Wernersson S, Reimer JM, Poorafshar M, Karlson U, Wermenstam N, Bengten E, Wilson M, Pilstrom L, Hellman L. |
Dev Comp Immunol. 2006;30(10):901-18. Epub 2005 Dec 27. |
PMID 16413608 |
|
Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity. |
Young JD, Hengartner H, Podack ER, Cohn ZA. |
Cell. 1986 Mar 28;44(6):849-59. |
PMID 2420467 |
|