TRPV6 exhibits unusual patterns of polymorphism and divergence in worldwide populations. |
Akey JM, Swanson WJ, Madeoy J, Eberle M, Shriver MD. |
Hum Mol Genet. 2006 Jul 1;15(13):2106-13. Epub 2006 May 22. |
PMID 16717058 |
|
Marked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel gene. |
Bianco SD, Peng JB, Takanaga H, Suzuki Y, Crescenzi A, Kos CH, Zhuang L, Freeman MR, Gouveia CH, Wu J, Luo H, Mauro T, Brown EM, Hediger MA. |
J Bone Miner Res. 2007 Feb;22(2):274-85. |
PMID 17129178 |
|
The role of TRPV6 in breast carcinogenesis. |
Bolanz KA, Hediger MA, Landowski CP. |
Mol Cancer Ther. 2008 Feb;7(2):271-9. Epub 2008 Feb 1. |
PMID 18245667 |
|
Ca2+-selective transient receptor potential V channel architecture and function require a specific ankyrin repeat. |
Erler I, Hirnet D, Wissenbach U, Flockerzi V, Niemeyer BA. |
J Biol Chem. 2004 Aug 13;279(33):34456-63. Epub 2004 Jun 10. |
PMID 15192090 |
|
Expression of the Ca2+-selective cation channel TRPV6 in human prostate cancer: a novel prognostic marker for tumor progression. |
Fixemer T, Wissenbach U, Flockerzi V, Bonkhoff H. |
Oncogene. 2003 Oct 30;22(49):7858-61. |
PMID 14586412 |
|
Calcium absorption across epithelia. |
Hoenderop JG, Nilius B, Bindels RJ. |
Physiol Rev. 2005 Jan;85(1):373-422. |
PMID 15618484 |
|
Parallel selection on TRPV6 in human populations. |
Hughes DA, Tang K, Strotmann R, Schoneberg T, Prenen J, Nilius B, Stoneking M. |
PLoS ONE. 2008 Feb 27;3(2):e1686. |
PMID 18301763 |
|
"Compositions Corresponding to a Calcium Transporter and Methods of Making and Using Same". |
Inventors: Matthias A. Hediger, Ji-Bin Peng and Edward M Brown. |
US patent # 6,534,642. |
|
TRPV6 is a Ca2+ entry channel essential for Ca2+-induced differentiation of human keratinocytes. |
Lehen'kyi V, Beck B, Polakowska R, Charveron M, Bordat P, Skryma R, Prevarskaya N. |
J Biol Chem. 2007 Aug 3;282(31):22582-91. Epub 2007 Jun 5. |
PMID 17550901 |
|
The human transient receptor potential vanilloid type 6 distal promoter contains multiple vitamin D receptor binding sites that mediate activation by 1,25-dihydroxyvitamin D3 in intestinal cells. |
Meyer MB, Watanuki M, Kim S, Shevde NK, Pike JW. |
Mol Endocrinol. 2006 Jun;20(6):1447-61. Epub 2006 Mar 30. |
PMID 16574738 |
|
Calcium fluxes in human trophoblast (BeWo) cells: calcium channels, calcium-ATPase, and sodium-calcium exchanger expression. |
Moreau R, Simoneau L, Lafond J. |
Mol Reprod Dev. 2003 Feb;64(2):189-98. |
PMID 12506351 |
|
Competitive regulation of CaT-like-mediated Ca2+ entry by protein kinase C and calmodulin. |
Niemeyer BA, Bergs C, Wissenbach U, Flockerzi V, Trost C. |
Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3600-5. |
PMID 11248124 |
|
Fast and slow inactivation kinetics of the Ca2+ channels ECaC1 and ECaC2 (TRPV5 and TRPV6). Role of the intracellular loop located between transmembrane segments 2 and 3. |
Nilius B, Prenen J, Hoenderop JG, Vennekens R, Hoefs S, Weidema AF, Droogmans G, Bindels RJ. |
J Biol Chem. 2002 Aug 23;277(34):30852-8. Epub 2002 Jun 19. |
PMID 12077127 |
|
Structural conservation of the genes encoding CaT1, CaT2, and related cation channels. |
Peng JB, Brown EM, Hediger MA. |
Genomics. 2001 Aug;76(1-3):99-109. |
PMID 11549322 |
|
Human calcium transport protein CaT1. |
Peng JB, Chen XZ, Berger UV, Weremowicz S, Morton CC, Vassilev PM, Brown EM, Hediger MA. |
Biochem Biophys Res Commun. 2000 Nov 19;278(2):326-32. |
PMID 11097838 |
|
CaT1 expression correlates with tumor grade in prostate cancer. |
Peng JB, Zhuang L, Berger UV, Adam RM, Williams BJ, Brown EM, Hediger MA, Freeman MR. |
Biochem Biophys Res Commun. 2001 Apr 6;282(3):729-34. |
PMID 11401523 |
|
The human TRPV6 channel protein is associated with cyclophilin B in human placenta. |
Stumpf T, Zhang Q, Hirnet D, Lewandrowski U, Sickmann A, Wissenbach U, Dorr J, Lohr C, Deitmer JW, Fecher-Trost C. |
J Biol Chem. 2008 Jun 27;283(26):18086-98. Epub 2008 Apr 29. |
PMID 18445599 |
|
Calcium channel TRPV6 is involved in murine maternal-fetal calcium transport. |
Suzuki Y, Kovacs CS, Takanaga H, Peng JB, Landowski CP, Hediger MA. |
J Bone Miner Res. 2008 Aug;23(8):1249-56. |
PMID 18348695 |
|
Mechanisms and regulation of epithelial Ca2+ absorption in health and disease. |
Suzuki Y, Landowski CP, Hediger MA. |
Annu Rev Physiol. 2008;70:257-71. |
PMID 17850211 |
|
Gain-of-function haplotype in the epithelial calcium channel TRPV6 is a risk factor for renal calcium stone formation. |
Suzuki Y, Pasch A, Bonny O, Mohaupt MG, Hediger MA, Frey FJ. |
Hum Mol Genet. 2008 Jun 1;17(11):1613-8. Epub 2008 Feb 13. |
PMID 18276610 |
|
Duodenal calcium absorption in vitamin D receptor-knockout mice: functional and molecular aspects. |
Van Cromphaut SJ, Dewerchin M, Hoenderop JG, Stockmans I, Van Herck E, Kato S, Bindels RJ, Collen D, Carmeliet P, Bouillon R, Carmeliet G. |
Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13324-9. Epub 2001 Oct 30. |
PMID 11687634 |
|
Expression of CaT-like, a novel calcium-selective channel, correlates with the malignancy of prostate cancer. |
Wissenbach U, Niemeyer BA, Fixemer T, Schneidewind A, Trost C, Cavalie A, Reus K, Meese E, Bonkhoff H, Flockerzi V. |
J Biol Chem. 2001 Jun 1;276(22):19461-8. Epub 2001 Feb 2. |
PMID 11278579 |
|
Calcium-selective ion channel, CaT1, is apically localized in gastrointestinal tract epithelia and is aberrantly expressed in human malignancies. |
Zhuang L, Peng JB, Tou L, Takanaga H, Adam RM, Hediger MA, Freeman MR. |
Lab Invest. 2002 Dec;82(12):1755-64. |
PMID 12480925 |
|