Atlas of Genetics and Cytogenetics in Oncology and Haematology


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EDUCATIONAL ITEMS in HUMAN GENETICS

Table of Content


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DNA and RNA
DNA, Molecular Structure
Messenger RNA, Structure
Ribosomal RNA, Structure
DNA Mutations
Nomenclature for mutations
DNA Replication
DNA Repair Systems
DNA Replication

Gene and Nucleus
Gene Structure
Transcription
Transcription and Traduction:
Amino Acids Structure, Genetic Code
Protein, Structure
Post Traduction Modifications
Proteins, main Functions - Reminder
Gene Example: Immunoglobulin
Gene Example: Hemoglobin
Gene Example: Developmental genes
Chromatin
Heterochromatin
Nucleus Architecture
Chromosome Ultrastructure
Centromeres
Telomeres

Cell Biology
Signal Transduction
Transcription Factors
Cell Cycle

Cell divisions
Mitosis
Meiosis

Methods in Genetics

Population Genetics
Hardy-Weinberg Model
Consanguinity
Selection
Mutations
Evolution
Mendelian and non Mendelian Inheritance
Autosomal Dominant Inheritance
Autosomal Recessive Inheritance
X Linked Inheritance
Multifactorial Traits
Mitochondrial Inheritance
Genomic Imprinting
Uniparental disomy
Genetic linkage
Diseases Examples: Cystis fibrosis
Diseases Examples: ..
Risk Calculation

Chromosomes
Chromosome abnormalities
Formation of chromosome aberrations
Balanced rearrangements and abnormal phenotype
Karyotype indications
Sex Chromosome evolution

Constitutional chromosome diseases
Reminder in Embryology and Dysmorphology
Trisomy 21
Other constitutional chromosome diseases
Other autosomes diseases
Dysgonosomies and related syndromes
Other chromosome imbalances
Chromosome aberrations: clinics, an overview
Microdeletions: phenotype and behaviour

Malignancies
Cancer Genes
Chromosomes, Leukaemias, Solid Tumors,Hereditary Cancers
Cancer prone diseases

Prevention in Genetics
Genetic Counselling
Prenatal Diagnosis
Neonatal Screening
Genetics and Public Health

Ethics
Genome and society
Ethical issues in cancer genetics

Glossary
Genetic Glossary



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