Chromosome

Chromosome : G-banding, diagram and R-banding - Claude Léonard, Jean-Loup Huret

Chromosome diagrams ISCN 2009 - Courtesy Nicole Chia

Alteration Genes Involved Chr/Band Chr/Band References
Isolated tetrasomy 8 in AML, MDS and MPD Link to Pubmed
NUP214/ABL1 fusion gene on amplified episomes p Link to Pubmed
Y loss in leukemia Link to Pubmed
11q23 rearrangements (KMT2A) in leukaemia Link to Pubmed
12p abnormalities in myeloid malignancies Link to Pubmed
12p rearrangements (ETV6) in ALL Link to Pubmed
3q26 rearrangements (MECOM) in myeloid malignancies Link to Pubmed
11q23 rearrangements (KMT2A) in therapy related leukaemias Link to Pubmed
9p Rearrangements in ALL Link to Pubmed
+X solely in myeloid malignancies Link to Pubmed
15q13-15 Rearrangements Link to Pubmed
+13,+13 or tetrasomy 13 Link to Pubmed
11q23 rearrangements (KMT2A) in childhood acute lymphoblastic leukemia Link to Pubmed
r(8) Link to Pubmed
1q triplication in hematologic malignancies Link to Pubmed
Unbalanced whole-arm translocation der(1;10)(q10-q11;p10-p12) Link to Pubmed
Unbalanced whole-arm translocation der(1;13) in hematologic malignancies Link to Pubmed
+X solely in lymphomas Link to Pubmed
12p rearrangements in CLL Link to Pubmed
dup(1q) in ALL1 q Link to Pubmed
del(1p)1 p Link to Pubmed
dup(1)(q11-q44) in myeloid malignancies1 q11-q44 Link to Pubmed
1q translocations (unbalanced) in myeloid malignancies1 q Link to Pubmed
1q rearrangements in multiple myeloma1 q Link to Pubmed
+2 or trisomy 22 Link to Pubmed
inv(2)(p23q35)ATIC::ALK2 p23q35 Link to Pubmed
inv(3)(p24q26)?::MECOM3 p24q26 Link to Pubmed
inv(3)(q21q26)RPN1::MECOM3 q21q26 Link to Pubmed
i(3)(q10) in non-Hodgkins lymphoma (NHL)3 q10 Link to Pubmed
3q27 rearrangements (BCL6) in non Hodgkin lymphomat(3;Var)(q27;Var) in non Hodgkin lymphoma3 q27 Link to Pubmed
Inv(3)(q21q26)GATA2::MECOM3 q21q26 Link to Pubmed
+3 or trisomy 3 in non Hodgkins lymphoma (NHL)3 Link to Pubmed
inv(3)(p12q26)?::MECOM3 p12q26 Link to Pubmed
inv(3)(q23q26)?::MECOM3 q23q26 Link to Pubmed
i(4p) in myeloid malignancies4 p Link to Pubmed
+4 or trisomy 44 Link to Pubmed
i(5)(p10) in acute myeloid leukemia5 p10 Link to Pubmed
i(5)(p10) in hematological malignancies5 p10 Link to Pubmed
del(5q) in myeloid neoplasms5 q Link to Pubmed
del (5q) solely in Myelodysplastic syndrome5 q Link to Pubmed
+5 or trisomy 55 Link to Pubmed
del(6q) abnormalities in lymphoid malignancies6 q Link to Pubmed
inv(6)(p25q13)6 p25q13 Link to Pubmed
del(6q)6 q Link to Pubmed
del(6p) (loss of JARID2 and DTNBP1) in myeloid malignances6 q Link to Pubmed
del(6q) in Multiple Myeloma6 q Link to Pubmed
+6 or trisomy 66 Link to Pubmed
i(6)(p10)6 p10 Link to Pubmed
i(7)(q10) in myeloid malignancies7 q10 Link to Pubmed
del(7)(p11-15)7 p11-15 Link to Pubmed
del(7q) in non-Hodgkins lymphoma (NHL)7 q Link to Pubmed
+7 or trisomy 7 (solely)7 Link to Pubmed
i(7)(q10)7 q10 Link to Pubmed
i(8)(q10) in acute myeloid leukaemia8 q10 Link to Pubmed
i(8)(q10) in ALL8 q10 Link to Pubmed
8p11 myeloproliferative syndrome (FGFR1)FGFR1::8 p11 Link to Pubmed
+8 or trisomy 88 Link to Pubmed
inv(8)(p11q13)KAT6A::NCOA28 p11q13 Link to Pubmed
del(9q)9 q Link to Pubmed
i(9)(p10)9 p10 Link to Pubmed
+9 or trisomy 99 Link to Pubmed
i(9q) in ALL9 q Link to Pubmed
+10 or trisomy 10 (solely)10 Link to Pubmed
inv(11)(q21q23)KMT2A::MAML211 q21q23 Link to Pubmed
inv(11)(q13q23)KMT2A::BTBD1811 q13q23 Link to Pubmed
inv(11)(p15q23)NUP98::KMT2A11 p15q23 Link to Pubmed
dup (11q) in myeloid malignancies11 q Link to Pubmed
11p15 rearrangements (NUP98) in treatment related leukemiaNUP98::11 p15 Link to Pubmed
11q23 rearrangements (KMT2A) in de novo childhood acute myeloid leukemiaKMT2A::11 q23 Link to Pubmed
del(11q) in non-Hodgkins lymphoma (NHL)11 q Link to Pubmed
+11 or trisomy 11 (solely)11 Link to Pubmed
inv(12)(p13q15)ETV6::PTPRR12 p13q15 Link to Pubmed
12p13 rearrangements (ETV6) in treatment related leukemia12 p13 Link to Pubmed
+12 or trisomy 1212 Link to Pubmed
del(13q) in myeloid malignancies13 q Link to Pubmed
del(13q) in ALL13 q Link to Pubmed
del(13q) in chronic lymphocytic leukemia13 q Link to Pubmed
del (13q)13 q Link to Pubmed
del(13q) in chronic lymphoproliferative diseases13 q Link to Pubmed
del(13q) in non-Hodgkins lymphoma13 q Link to Pubmed
del(13q) in multiple myeloma13 q Link to Pubmed
+13 or trisomy 1313 Link to Pubmed
+14 or trisomy 14 (solely)14 Link to Pubmed
+15 or trisomy 15 (as sole autosomal abnormality)15 Link to Pubmed
inv(16)(p13q24)CBFA2T3::GLIS216 p13q24 Link to Pubmed
+16 or trisomy 16 (solely)16 Link to Pubmed
del(17p) in myeloid malignancies17 p Link to Pubmed
del(17p) in non-Hodgkins lymphoma (NHL)17 Link to Pubmed
i(17q) solely in myeloid malignanciessolely::17 q Link to Pubmed
inv(18)(p11q21)18 p11q21 Link to Pubmed
del(18)(p11)18 p11 Link to Pubmed
+18 or trisomy 18 in lymphoproliferative disorders18 Link to Pubmed
i(18)(q10)18 q10 Link to Pubmed
+19 or trisomy 1919 Link to Pubmed
del(20q) in myeloid malignancies20 q Link to Pubmed
ider(20q) in Myeloid Malignancies20 q Link to Pubmed
-20 or monosomy 2020 Link to Pubmed
+20 or trisomy 20 (solely)20 Link to Pubmed
dup(21q) amplified (RUNX1)::RUNX121 q Link to Pubmed
der(21)t(1;21)(q11-12;p11-13))21 1 21 Link to Pubmed
der(21)t(1;21)(q21-32;p11-13)21 1 21 Link to Pubmed
21q22 rearrangements (RUNX1) in treatment related leukemiaRUNX1::21 q22 Link to Pubmed
+21 or trisomy 2121 Link to Pubmed
-21 or monosomy 21 (solely)21 Link to Pubmed
i(22)(q10) in myeloid malignancies22 q10 Link to Pubmed
+22 or trisomy 22 (solely?)22 Link to Pubmed
i(X)(q10) in male patientsX q10 Link to Pubmed
i(Xq10) in female patientsX q10 Link to Pubmed
i(X)(p10) in female patientsX p10 Link to Pubmed
Y loss in leukemiaY Link to Pubmed