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Chromosome 15

Chromosome 15 : G-banding, diagram and R-banding - Claude Léonard, Jean-Loup Huret
Chromosome 15 diagrams ISCN 2009 - Courtesy Nicole Chia

Leukaemia     

dic(1;15)(p11;p11)
+15 or trisomy 15 (as sole autosomal abnormality)
t(5;15)(q33;q22) TP53BP1/PDGFRB
t(9;15)(p13;q24) PAX5/PML
t(11;15)(q23;q14) KMT2A/CASC5
t(12;15)(p13;q25) ETV6/NTRK3
t(14;15)(q32;q11) IGH/NBEAP1
t(15;17)(q22;q21) in treatment related leukemia
t(15;17)(q24;q21) PML/RARA
t(15;21)(q22;q22) RUNX1/?

Solid Tumors     

t(7;15)(p21;q21) HMGN2P46/ETV1
t(9;15)(q22;q21) TCF12/NR4A3
t(9;15)(q22;q21) TCF12/NR4A3
t(12;15)(p13;q25) ETV6/NTRK3
t(12;15)(p13;q25) ETV6/NTRK3
t(12;15)(p13;q26) ETV6/NTRK3
t(15;19)(q14;p13) BRD4/NUTM1

Cancer prone diseases     

Bloom syndrome

All Genes by Location (Kb)

Chromosome 15 by location

Losses / Amplicons     

BONE/SOFT TISSUE



External links     

  • Chromosome 15 - HUGO Chromosomes
  • Chromosome 15 - GoldenPath - Santa Cruz
  • Chromosome 15 - Ensembl Project
  • Chromosome 15 - Map View - NCBI
  • Chromosome 15 - OMIM Gene map
  • Chromosome 15 - Genomic Variants
  • Chromosome 15 - HAPMAP Project
  • Chromosome 15 - Genome Channel - ORNL
  • Chromosome 15 - LaunchPad HGMIS
  • Chromosome 15 - Human Protein Atlas
  • Chromosome 15 - Array BAC clone - Roswell Park Cancer Institute
  • Chromosome 15 - Human BAC Resource (NCBI)
  • Chromosome 15 FISH-mapped BACs (CCAP)
  • Genetic Maps (CHLC)
  • YACs mapped by FISH (Bari)
  • PCP (Partial Chromosome Paints) (Bari)
  • Mouse homology - OMIM - NCBI
  • Chromosome 15 Cancer GeneWeb
  • Human Proteomics Initiative (UniProt)
  • Cytogenetic marker FISH (Abbott)
  • FISH Probes DAKO
  • SureFISH Probes
  • CytoCell
  • Kreatech Diagnostic/

  • Genes

    Annotated genes
    Ordered by Name Ordered by Location
     Kb pter-qter
    ADAM10 58887.403 15q2
    ANP32A 69070.875 15q23
    AVEN 34158.428 15q13.1
    BLM 91260.558 15q26.1
    BUB1B 40453.210 15q15
    CASC5 40886.447 15q14
    CEMIP 81071.684 15q25.1
    COPS2 49417.471 15q21.2
    CTSH 79214.092 15q25.1
    FURIN 91414.769 15q26.1
    GCNT3 59903.982 15q22
    IGF1R 99191.768 15q26.3
    ITGA11 68594.042 15q22.3-q23
    KIAA0101 64657.211 15q22
    MAPK6 52311.411 15q21
    MIR211 31357.235 15q13.3
    NBEAP1 20874.797 15q11.2
    NEIL1 75639.960 15q33.33
    NTRK3 88520.596 15q24-q25
    NUTM1 34635.516 15q14
    PIAS1 68346.572 15q
    PKM 72491.370 15q23
    PLCB2 40580.098 15q15.1
    PML 74287.014 15q24.1
    RASGRF1 79252.289 15q24
    SHC4 49115.934 15q21.1-q21.2
    SPINT1 41136.643 15q13.3
    TCF12 57210.833 15q21
    THBS1 39873.280 15q15
    TRPM1 31293.264 15q13.3
    TYRO3 41851.220 15q15.1-q21.1
    UBE3A 25582.396 15q11.2
    Other genes
    possibly implicated
    in cancer
    Ordered by Name Ordered by Location
     Kb pter-qter
    ACAN 89346.674 15q26.1
    ACTC1 35080.297 15q14
    ADAL 43622.554 15q15.3
    ADAMTS17 100511.643 15q24
    ADAMTS7 79051.545 15q25.1
    ADAMTSL3 84322.838 15q25.2
    ADPGK 73043.708 15q24.1
    AEN 89164.527 15q26.1
    AGBL1 86685.242 15q25.3
    AKAP13 86163.181 15q24-q25
    ALDH1A2 58245.622 15q21.2
    ALDH1A3 101419.897 15q26
    ANPEP 90328.126 15q25-q26
    ANXA2 60639.350 15q22.2
    APBA2 29213.840 15q11-q12
    APH1B 63569.749 15q22.2
    AQP9 58430.408 15q
    ARHGAP11A 32907.345 15q13.3
    ARID3B 74833.548 15q24
    ARIH1 72766.667 15q24
    ARNT2 80696.692 15q25.1
    ARPP19 52839.432 15q11.2
    ATP10A 25923.860 15q12
    ATP8B4 50150.435 15q21.2
    B2M 45003.685 15q21-q22.2
    BCL2A1 80253.232 15q24.3
    BCL2L10 52401.822 15q21
    BLOC1S6 45879.417 15q21.1
    BMF 40380.092 15q14
    BNIP2 59955.062 15q21.3
    C15orf48 45722.727 15q21.1
    CA12 63615.730 15q22
    CALML4 68483.043 15q22.31
    CAPN3 42651.698 15q15.1
    CASC4 44580.909 15q15.1
    CCNB2 59397.284 15q21.3
    CCNDBP1 43477.466 15q14-q15
    CCPG1 55647.421 15q21.1
    CD276 73976.622 15q23-q24
    CHAC1 41245.636 15q15.1
    CHD2 93443.551 15q26
    CHEK2P2 20487.997 15q11.1
    CHP1 41523.437 15q13.3
    CHRFAM7A 30653.443 15q13.2
    CHRNA3 78887.647 15q24
    CHRNA5 78857.862 15q24
    CHRNA7 32322.686 15q13.3
    CHRNB4 78916.636 15q24
    CHSY1 101715.928 15q26.3
    CIB1 90773.477 15q25.3-q26
    CIB2 78396.948 15q24
    CKMT1A 43985.084 15q15
    CKMT1B 43885.252 15q15
    CLK3 74907.335 15q24
    COX5A 75212.617 15q25
    CPEB1 83211.951 15q25.1
    CRABP1 78632.666 15q24
    CRTC3 91073.118 15q26.1
    CSK 75074.425 15q24.1
    CSNK1G1 64457.716 15q22.1-q22.31
    CSPG4 75966.663 15q24.2
    CT62 71402.583 15q23
    CYFIP1 22955.755 15q11
    CYP11A1 74630.103 15q23-q24
    CYP19A1 51500.254 15q21.1
    CYP1A1 75011.883 15q24.1
    CYP1A2 75041.184 15q24.1
    DAPK2 64199.235 15q22.1
    DENND4A 65952.957 15q22.31
    DET1 89055.714 15q25.3
    DLL4 41221.531 15q14
    DMXL2 51739.921 15q21.2
    DNAJA4 78556.989 15q24.1
    DNAJC17 41060.067 15q15.1
    DPP8 65737.998 15q22
    DTWD1 49913.226 15q21.2
    DUOX1 45422.192 15q21
    DUOX2 45384.852 15q15.3-q21
    DUOXA1 45409.564 15q21.1
    DUOXA2 45406.523 15q21.1
    DUT 48623.621 15q21.1
    DYX1C1 55722.506 15q21.1
    EID1 49170.290 15q21.1
    EIF2AK4 40226.325 15q13.3
    EIF3J 44829.266 15q21.1
    ELL3 44064.798 15q15.1
    ETFA 76508.629 15q23-q25
    FAN1 31196.076 15q13.2-q13.3
    FANCI 89787.194 15q26.1
    FBN1 48700.503 15q21.1
    FBXL22 63889.552 15q22.1
    FEM1B 68570.141 15q22
    FES 91428.276 15q25-qter
    FGF7 49715.375 15q21.2
    FMN1 33057.745 15q13.3
    FOXB1 60296.421 15q22
    FRMD5 44162.959 15q15.3
    FSIP1 39892.232 15q14
    GABRB3 26788.694 15q12
    GLCE 69452.973 15q23
    GLDN 51633.713 15q15.3
    GNB5 52413.123 15q21.2
    GOLGA6A 74362.198 15q24.1
    GOLGA6B 72947.038 15q24.1
    GOLGA6C 75550.899 15q24.2
    GOLGA6D 75575.182 15q24.2
    GREM1 33010.205 15q13.3
    HAPLN3 89420.519 15q26.1
    HDC 50534.146 15
    HERC1 63900.817 15q22
    HERC2 28356.183 15q13
    HEXA 72635.778 15q24.1
    HMG20A 77713.243 15q24
    HMGN2P46 45803.334 15q15.1
    HSP90B2P 99797.730 15q25-q26
    HYKK 78799.906 15q25.1
    IDH2 90627.211 15q21-qter
    IGDCC4 65673.825 15q22.31
    IL16 81489.219 15q26.3
    IMP3 75931.426 15q24
    INO80 41271.079 15q15.1
    IQGAP1 90931.473 15q26.1
    IREB2 78730.518 15
    ISG20 89182.039 15q26
    ITPKA 41786.056 15q15.1
    KIF23 69706.585 15q23
    KLF13 31619.083 15q13.3
    LARP6 71123.863 15q23
    LCMT2 43619.974 15q15.3
    LCTL 66839.806 15q21.3
    LDHAL6B 59499.015 15q21.3
    LEO1 52230.222 15q21.2
    LINGO1 77905.369 15q24
    LIPC 58724.175 15q21-q23
    LMAN1L 75105.194 15q24.1
    LOC100291666 100038.019 -
    LOC440311 95398.592 15q26.2
    LOXL1 74218.789 15q24-q25
    LPCAT4 34651.089 15q14
    LTK 41795.840 15q15.1-q21.1
    MAN2C1 75648.133 15q11-qter
    MAP2K1 66679.211 15q22.1-q22.33
    MAP2K5 67841.342 15q22.31
    MAPKBP1 42066.632 15q15.1
    MEF2A 100106.133 15q26
    MEIS2 37183.222 15q14
    MESDC1 81293.295 15q13
    MESDC2 81268.095 15q13
    MESP2 90319.589 15q26.1
    MEX3B 82334.119 15q25.1
    MFGE8 89441.914 15q25
    MGA 41952.610 15q15
    MIR1233-1 34674.270 15
    MIR184 79502.130 15q25.1
    MIR190A 63116.156 15q22.2
    MIR628 55665.138 15q21.3
    MIR630 72879.558 15q24.1
    MIR7-2 89155.056 15q26.1
    MIR9-3 89911.248 15q26.1
    MORF4L1 79165.123 15q25.1
    MYO5A 52599.480 15q21
    NDN 23930.554 15q11-q12
    NDNL2 29560.353 15q13.1
    NEDD4 56119.117 15q
    NEO1 73344.825 15q22.3-q23
    NIPA2 23004.684 15q11.2
    NOX5 69307.034 15q22.31
    NPTN-IT1 73859.279 15q24.1
    NR2E3 72102.888 15q23
    NR2F2 96869.157 15q26
    NRG4 76234.328 15q23
    NUSAP1 41624.892 15q14
    OCA2 28000.023 15q12
    OIP5 41601.466 15q14
    ONECUT1 53049.160 15q21.3
    OTUD7A 31775.329 15q13.1
    PAK6 40509.629 15q14
    PAQR5 69606.742 15q22.31
    PARP6 72533.522 15q22
    PCSK6 101844.133 15q26
    PDCD7 65409.717 15q22.2
    PDIA3 44038.590 15q15
    PEAK1 77400.498 15q24.3
    PIF1 65107.829 15q22.1
    PIGB 55611.133 15q21.3
    PLIN1 90207.600 15q26
    POLG 89859.536 15q24
    PPIB 64448.014 15q21-q22
    PPP1R14D 41107.643 15q11.2-q14
    PRC1 91509.268 15q26.1
    PTPN9 75759.462 15q23
    PWAR1 25380.789 15q11.2
    RAB11A 66161.797 15q22.31
    RAB27A 55495.164 15q15-q21.1
    RAB8B 63481.728 15q22
    RAD51 40987.378 15q15.1
    RASGRP1 38780.302 15q15
    RASL12 65345.675 15q11.2-q22.33
    RBPMS2 65032.095 15q22.3
    RCN2 77223.962 15q22.33-q24.1
    RGMA 93586.636 15q26.1
    RHOV 41164.412 15q13.3
    RMDN3 41028.086 15q15.1
    RNF111 59279.865 15q21
    RORA 60780.483 15q21-q22
    RPLP1 69745.159 15q22
    RPS27L 63445.539 15q21.3
    RTF1 41709.302 15q14
    RYR3 33603.177 15q14-q15
    SCAMP2 75137.197 15q23-q25
    SCG3 51973.550 15
    SCG5 32933.870 15q13-q14
    SECISBP2L 49280.835 15q21.1
    SEMA6D 47476.403 15q21.1
    SERF2 44084.040 15q15.1
    SH3GL3 84116.091 15q24
    SIN3A 75661.720 15q22.33
    SKOR1 68112.042 15q23
    SLC12A1 48498.498 15q15-q21
    SLC12A6 34522.197 15q13
    SLC28A1 85427.892 15q25.3
    SLC30A4 45774.680 15q21.1
    SLCO3A1 92396.938 15q26
    SLTM 59171.244 15q21.3
    SMAD3 67418.054 15q21-q22
    SMAD6 67000.930 15q21-q22
    SNAP23 42787.504 15q14
    SNRPN 25200.135 15q11.2
    SNURF 25200.135 15q11.2
    SNX1 64388.083 15q22.31
    SORD 45315.302 15q15-q21.1
    SPG11 44854.894 15q13-q15
    SPG21 65255.362 15q21-q22
    SPRED1 38545.052 15q14
    SQRDL 45923.346 15q21.1
    ST20 80191.182 15q25.1
    ST8SIA2 92937.140 15q26
    STARD9 42867.857 15q14
    STOML1 74275.559 15q24-q25
    SV2B 91643.182 15q26.1
    SYNM 99645.286 15q26.3
    THSD4 71839.541 15q23
    TICRR 90118.818 15q26.1
    TJP1 29992.357 15q13
    TLE3 70340.130 15q22
    TLN2 62939.510 15q15-q21
    TMED3 79603.491 15q24-q25
    TMOD2 52043.758 15q21.2
    TMOD3 52121.825 15q21.1-q21.2
    TNFAIP8L3 51348.799 15q21.2
    TP53BP1 43699.412 15q15-q21
    TPM1 63334.838 15q22.1
    TRPM7 50849.352 15q21
    TTBK2 43036.542 15q15.2
    UACA 70946.893 15q22-q24
    UBE2Q2 76136.385 15q24.2
    ULK3 75128.457 15q24.1
    UNC45A 91473.410 15q26.1
    USP3 63796.710 15q22.3
    USP8 50716.574 15q21.1
    VIMP 101812.387 15q26.3
    VPS39 42450.899 15q14
    WDR72 53805.938 15q21.3
    WDR76 44119.112 15q15.3
    ZFAND6 80351.910 15q24.3
    ZFYVE19 41099.274 15q14
    ZNF280D 56922.374 15q21.2
    ZNF592 85291.818 15q25.2

    GeneCards  

    Contributor(s)

    WrittenJul 2004Philippe Dessen, Sakari Knuutila, Jean-Loup Huret
    UpdatedAug 2014Philippe Dessen, Jean-Loup Huret

    Citation

    This paper should be referenced as such :
    Dessen P, Knuutila S, Huret JL . Chromosome . Atlas Genet Cytogenet Oncol Haematol. Jul 2004 .
    URL : http://AtlasGeneticsOncology.org/Indexbychrom/idxa_15.html
    Dessen P, Huret JL . Chromosome . Atlas Genet Cytogenet Oncol Haematol. Aug 2014 .
    URL : http://AtlasGeneticsOncology.org/Indexbychrom/idxa_15.html
    © Atlas of Genetics and Cytogenetics in Oncology and Haematology
    indexed on : Fri Aug 29 17:50:59 CEST 2014


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