Atlas of Genetics and Cytogenetics in Oncology and Haematology


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Chromosome 5

Chromosome 5 : G-banding, diagram and R-banding - Claude Léonard, Jean-Loup Huret
Chromosome 5 diagrams ISCN 2009 - Courtesy Nicole Chia

Leukaemia     

del(5q) in myeloid neoplasms
+5 trisomy 5
i(5)(p10) in acute myeloid leukemia
ins(5;11)(q31;q13q23) KMT2A/AFF4
t(1;5)(p32;q31) ?/TAL1
t(1;5)(q22;q33) PDE4DIP/PDGFRB
t(2;5)(p23;q35) NPM1/ALK
t(2;5)(p23;q35) SQSTM1/ALK
t(2;5)(p21;q33) SPTBN1/PDGFRB
t(3;5)(p21;q32) RBM6/CSF1R
t(3;5)(q21;q31)
t(3;5)(q25;q34) NPM1/MLF1
t(3;5)(q26;q34) ?/MECOM
t(4;5)(q21;q33) PRKG2/PDGFRB
t(4;5)(q31;q31)
t(5;7)(q33;q11) HIP1/PDGFRB
t(5;7)(q35;q21) TLX3/CDK6
t(5;9)(q14.1;p24) SSBP2/JAK2
t(5;9)(q32;p24) KANK1/PDGFRB
t(5;9)(q33;q22) ITK/SYK
t(5;10)(q33;q21) CCDC6/PDGFB
t(5;11)(q31;q23) KMT2A/ARHGAP26
t(5;11)(q33;p13) CAPRIN1/PDGFRB
t(5;11)(q35;p15.5) NUP98/NSD1
t(5;11)(q35;q12) NSD1/FEN1
t(5;12)(p13;p13) NIPBL/ETV6
t(5;12)(q13;p13) ?/ETV6
t(5;12)(q31;p13) ETV6/ACSL6 in MDS,AML and AEL
t(5;12)(q33;p13) ETV6/PDGFRB
t(5;12)(q33;p13) ERC1/PDGFRB
t(5;12)(q33;q24) GIT2/PDGFRB
t(5;14)(q31;q32) IGH/IL3
t(5;14)(q33;q24) NIN/PDGFRB
t(5;14)(q33;q32) PDGFRB/TRIP11
t(5;14)(q33;q32) PDGFRB/CCDC88C
t(5;14)(q35;q11) TRD/NKX2-5
t(5;14)(q35;q32) BCL11B/TLX3
t(5;14)(q35;q32.2) BCL11B/TLX3 and NKX2-5
t(5;15)(q33;q22) TP53BP1/PDGFRB
t(5;16)(q32;p13) NDE1/PDGFRB
t(5;16)(q33;q22)
t(5;17)(q13;q21)
t(5;17)(q33;p13) RABEP1/PDGFRB
t(5;17)(q33;p11.2) SPECC1/PDGFRB
t(5;17)(q35;q21) NPM1/RARA
t(5;21)(q13;q22) RUNX1/?

Solid Tumors     

t(1;5)(q42;q32) IRF2BP2/CDX1
t(5;5)(q23;q35) LMAN2/AP3S1
t(5;5)(q31;q31) WDR55/DND1
t(5;5)(q31;q35) SPOCK1/TBC1D9B
t(5;8)(p15;q13) AHRR/NCOA2
t(5;8)(p15;q13) AHRR/NCOA2
t(5;12)(q33;q14) HMGA2/EBF1
t(5;12)(q33;q14) HMGA2/EBF1
t(5;12)(q33;q14) HMGA2/EBF1

Cancer prone diseases     

Familial adenomatous polyposis (FAP)
Cockayne syndrome
Hereditary desmoid disease.
Oculocutaneous Albinism
Paget's disease of bone
Sotos syndrome (SOS)

All Genes by Location (Kb)

Chromosome 5 by location

Losses / Amplicons     

BONE/SOFT TISSUE



External links     

  • Chromosome 5 - HUGO Chromosomes
  • Chromosome 5 - GoldenPath - Santa Cruz
  • Chromosome 5 - Ensembl Project
  • Chromosome 5 - Map View - NCBI
  • Chromosome 5 - OMIM Gene map
  • Chromosome 5 - Genomic Variants
  • Chromosome 5 - HAPMAP Project
  • Chromosome 5 - Genome Channel - ORNL
  • Chromosome 5 - LaunchPad HGMIS
  • Chromosome 5 - Human Protein Atlas
  • Chromosome 5 - Array BAC clone - Roswell Park Cancer Institute
  • Chromosome 5 - Human BAC Resource (NCBI)
  • Chromosome 5 FISH-mapped BACs (CCAP)
  • Genetic Maps (CHLC)
  • YACs mapped by FISH (Bari)
  • PCP (Partial Chromosome Paints) (Bari)
  • Mouse homology - OMIM - NCBI
  • Chromosome 5 Cancer GeneWeb
  • Chromosome 5 GeneCards (Weizmann)
  • Human Proteomics Initiative (UniProt)
  • Cytogenetic marker FISH (Abbott)
  • FISH Probes DAKO
  • SureFISH Probes
  • CytoCell
  • Kreatech Diagnostic/

  • Genes

    Annotated genes
    Ordered by Name Ordered by Location
     Kb pter-qter
    ADAMTS12 33527.287 5q35
    ADRB2 148206.156 5q31-q32
    AFF4 132211.071 5q31
    APC 112073.556 5q21-q22
    ARHGAP26 142150.292 5q31
    CARTPT 71014.990 5q13.2
    CCNB1 68462.837 5q12
    CD74 149781.200 5q32
    CPEB4 173315.331 5q21
    CSF1R 149432.854 5q32
    CSNK1A1 148875.457 5q32
    CXXC5 139028.301 5q31.3
    DAB2 39371.776 5p13
    DBN1 176883.614 5q35.3
    DUSP1 172195.093 5q35.1
    EDIL3 83236.414 5q14
    EGR1 137801.181 5q23-q31
    ENC1 73923.231 5q13
    ERCC8 60169.659 5q12.1
    FGF1 141971.743 5q31.3-q33.2
    FGFR4 176513.873 5q33-qter
    FNIP1 130977.407 5q23.3
    FST 52776.264 5q11.2
    GNB2L1 180663.928 5q35.3
    GZMA 54398.474 5q11-q12
    HDAC3 141000.443 5q31.1-q31.2
    IL3 131396.347 5q23-q31
    IL7R 35856.977 5p13
    IRF1 131817.301 5q23-q31
    ITK 156607.907 5q31-q32
    LIFR 38475.065 5p13-p12
    LOX 121398.890 5q23.3-q31.2
    MAPK9 179673.028 5q35
    MCC 112357.796 5q21-q22
    MIR143 148808.481 5q32
    MIR145 148810.209 5q32
    MIR449A 54466.360 5q11.2
    MSH3 79950.467 5q11-q12
    MSX2 174151.575 5q35.2
    NKX2-5 172659.107 5q34
    NPM1 170814.708 5q35.1
    NSD1 176560.833 5q35
    PDCD6 271.736 5p15.33
    PDGFRB 149493.402 5q33.1
    PIK3R1 67588.396 5q13.1
    PRLR 35055.802 5p14-p13
    PTTG1 159848.917 5q35.1
    SEPP1 42799.982 5q31
    SLIT3 168088.738 5q35
    SPINK7 147691.990 5q32
    TGFBI 135364.584 5q31
    TLX3 170736.288 5q35.1
    TRIO 14143.829 5p14-p15.1
    VCAN 82767.493 5q14.2-q14.3
    VDAC1 133307.566 5q31
    WWC1 167719.065 5q34
    Other genes
    possibly implicated
    in cancer
    Ordered by Name Ordered by Location
     Kb pter-qter
    ACSL6 131285.667 5q31
    ADAM19 156904.312 5q33.3
    ADAMTS16 5140.443 5p15
    ADAMTS6 64444.563 5q13
    ADCY2 7396.343 5p15.3
    ADRA1B 159343.740 5q33.3
    AFAP1L1 148651.401 5q33.1
    AHRR 304.291 5p15.33
    ALDH7A1 125877.533 5q31
    AMACR 33987.091 5p13.2
    ANKH 14704.909 5p15.2
    ANKHD1 139781.399 5q31.3
    ANXA2R 43039.182 5p12
    ANXA6 150480.267 5q33.1
    AP3S1 115177.619 5q22
    ARAP3 141032.968 5q31.3
    ARHGEF28 72921.983 5q13.2
    ARRDC3 90664.541 5q14.3
    ATG10 81267.844 5q14.1
    ATG12 115163.894 5q21-q22
    ATOX1 151122.383 5q32
    ATP10B 159990.127 5q34
    B4GALT7 177027.119 5q35.1-q35.3
    BASP1 17216.932 5p15.1
    BHMT2 78365.547 5q13
    BHMT 78407.604 5q14.1
    BNIP1 172571.445 5q33-q34
    BRD8 137492.573 5q31
    BTF3 72794.250 5q13.3
    C1QTNF2 159774.775 5q33.3
    C1QTNF3 34017.963 5p13
    C7 40909.599 5
    C9 39284.378 5p14-p12
    CAMK2A 149599.054 5
    CAMK4 110559.947 5q22.1
    CAMLG 134074.170 5q23
    CANX 179125.930 5q35
    CARD6 40841.410 5p13.1
    CAST 95997.861 5q15
    CCL28 43381.600 5p12
    CCNG1 162864.577 5q32-q34
    CCNH 86690.079 5q13.3-q14
    CCNO 54526.981 5q11.2
    CCT5 10250.282 5p15.2
    CD14 140011.313 5q31.3
    CD180 66478.104 5q12
    CDC23 137523.337 5q31
    CDC25C 137620.954 5q31
    CDC42SE2 130599.702 5q31.1
    CDH12 21750.973 5p14.3
    CDH18 19473.155 5p14.3
    CDH6 31193.762 5p13.3
    CDHR2 175969.512 5q35.2
    CDK7 68530.622 5q12.1
    CDKL3 133634.115 5q31
    CDO1 115140.430 5q23.2
    CDX1 149546.344 5q32
    CENPH 68485.375 5p15.2
    CENPK 64813.593 5q12.3
    CHD1 98190.908 5q15-q21
    CHSY3 129240.523 5q13
    CKMT2 80529.139 5
    CLK4 178029.665 5q35
    CLPTM1L 1318.000 5p15.33
    CLTB 175819.456 5q35.2
    CNOT8 154238.198 5q31-q33
    COL23A1 177664.617 5q35.3
    COL4A3BP 74666.928 5q13.3
    CRHBP 76248.680 5q
    CSF2 131409.485 5q23-q31
    CSNK1G3 122847.793 5q23
    CTNNA1 138089.085 5q31.2
    CTNND2 10971.954 5p15.2
    CWC27 64064.755 5q12.3
    CXCL14 134906.371 5q31
    CYFIP2 156693.090 5q34
    DAP 10679.342 5p15.2
    DDX41 176938.578 5q35.3
    DDX4 55033.845 5p15.2-p13.1
    DDX46 134094.461 5q31.1
    DEPDC1B 59892.739 5q12
    DHFR 79922.045 5q11.2-q13.2
    DHX29 54552.073 5q11.2
    DIAPH1 140894.588 5q31
    DNAJC18 138745.892 5q31.2
    DND1 140050.381 5q31.3
    DOCK2 169064.251 5q35.1
    DOK3 176928.906 5q35
    DPYSL3 146770.371 5q32
    DROSHA 31400.602 5q11.2
    EBF1 158122.923 5q34
    EFNA5 106712.590 5q21
    EIF4EBP3 139927.251 5q31.3
    ELL2 95220.802 5q15
    ELOVL7 60047.616 5q12
    EMB 49692.031 5q11.1
    ERAP1 96110.188 5q15
    ERAP2 96211.644 5q15
    ERBB2IP 65222.382 5p14.3-q12.3
    ERGIC1 172261.223 5q35.1
    ESM1 54273.695 5q11
    ETF1 137841.782 5q31.2
    EXOC3 443.334 5p15.33
    F2R 76011.868 5q13
    F2RL1 76114.833 5q13
    F2RL2 75911.307 5q13
    FABP6 159626.048 5q23-q35
    FAM134B 16473.147 5p15.1
    FAM172A 92953.431 5q15
    FAM173B 10225.620 5p15.2
    FAM193B 176946.790 5q35
    FAT2 150883.653 5q33.1
    FBN2 127593.601 5q23-q31
    FBXL17 107194.734 5q21.3
    FBXL21 135266.006 5q31
    FBXL7 15501.547 5p15.1
    FBXO38 147763.498 5q33.1
    FBXO4 41925.356 5p12
    FCHO2 72251.808 5q13.2
    FCHSD1 141018.869 5q31.3
    FER 108083.523 5q21
    FGF10 44305.097 5p13-p12
    FGF18 170846.667 5q34
    FLT4 180034.753 5q34-q35
    FOXD1 72742.085 5q12-q13
    FOXI1 169532.917 5q34
    FTMT 121187.650 5q23.1
    FYB 39105.354 5p13.1
    G3BP1 151151.476 5q33.1
    GABRA1 161274.197 5q34
    GABRB2 160715.436 5q34
    GABRP 170210.723 5q35.1
    GDF9 132196.874 5q31.1
    GDNF 37812.779 5p13.1-p12
    GEMIN5 154266.976 5q34
    GFRA3 137588.069 5q31.1-q31.3
    GHR 42423.877 5p14-p12
    GLRX 95149.553 5q14
    GOLPH3 32124.824 5p13.2
    GPX3 150399.999 5q23
    GRIA1 152870.084 5q31.1
    GRK6 176853.687 5q35
    GTF2H2 70330.951 5q13.2
    GTF2H2B 70331.332 5q13.2
    GTF2H2C_2 68856.074 5q
    GTF2H2C 68856.051 5q13.2
    H2AFY 134670.071 5q31.1
    HAPLN1 82934.017 5q14.3
    HARS 140053.489 5q31.3
    HAVCR1 156456.531 5q33.2
    HAVCR2 156512.843 5q34
    HBEGF 139712.428 5q23
    HCN1 45255.052 5p12
    HEIH 180256.954 5q35.3
    HEXB 73980.969 5q13.3
    HINT1 130494.976 5q31.2
    HK3 176307.870 5q35.2
    HMGCR 74632.993 5q13.3-q14
    HMHB1 143191.726 5q32
    HMMR 162887.517 5q33.2-qter
    HNRNPH1 179041.179 5q35.3
    HRH2 175085.040 5q35.2
    HSD17B4 118788.138 5q2
    HSPA4 132387.662 5q31.1
    HSPA9 137890.571 5q31.1
    HSPB3 53751.431 5q11.2
    HTR1A 63255.875 5q11.2-q13
    HTR4 147861.115 5q31-q33
    IK 140027.384 5q31.3
    IL12B 158741.791 5q31.1-q33.1
    IL13 131993.865 5q31
    IL31RA 55149.150 5q11.2
    IL4 132009.678 5q23-q31
    IL5 131877.136 5q23-q31
    IL6ST 55230.925 5q11.2
    IL9 135227.935 5q31-q35
    IPO11 61714.711 5q12.1
    IQGAP2 75843.234 5q
    IRGM 150226.085 5q33.1
    IRX1 3596.168 5p15.33
    IRX2 2746.279 5p15.33
    IRX4 1877.541 5p15.33
    ISL1 50678.958 5q11.2
    ITGA1 52084.136 5q11.1
    ITGA2 52285.156 5q11.2
    JAKMIP2 146965.004 5q32
    JMY 78531.925 5q14.1
    KCNMB1 169805.165 5q34
    KDM3B 137688.285 5q31
    KIF20A 137514.417 5q31
    LARS 145492.589 5q32
    LCP2 169675.088 5q35.1
    LEAP2 132209.358 5q31.1
    LECT2 135282.600 5q31.1
    LMAN2 176758.563 5q35
    LMNB1 126112.845 5q23.2
    LNPEP 96271.346 5q15
    LPCAT1 1461.542 5p15.33
    LTC4S 179220.986 5q35
    LUCAT1 90598.803 5q14.3
    MAML1 179159.851 5q35
    MAP1B 71403.118 5q13
    MAP3K1 56110.900 5q11.2
    MARVELD2 68710.939 5q13.1
    MAST4 65892.176 5q12.3
    MAT2B 162932.534 5q34-q35
    MEF2C 88014.058 5q14.3
    MGAT1 180217.541 5q35.3
    MGAT4B 179224.598 5q35
    MIER3 56215.429 5q11.2
    MIR146A 159912.359 5q34
    MIR218-2 168195.151 5q34
    MIR340 179442.303 5q35.3
    MIR449B 54466.474 5q11.2
    MIR874 136983.261 5q31.2
    MIR9-2 87962.671 5q14.3
    MRPL36 1798.499 5p15.3
    MRPS30 44809.027 5q11
    MTMR12 32227.111 5p15.33
    MTRR 7869.217 5p15.31
    MYO10 16662.016 5p15.1-p14.3
    MYOT 137203.545 5q31.2
    MYOZ3 150040.403 5q33.2
    MZB1 138723.257 5q31.2
    NADK2 36192.691 5p13.2
    NAIP 70264.310 5q13.2
    NDST1 149887.674 5q33.1
    NDUFAF2 60240.956 5q12.1
    NDUFS4 52856.465 5q11.1
    NEUROG1 134869.972 5q23-q31
    NHP2 177576.465 5q35.3
    NIPBL 36876.861 5p13.2
    NKD2 1009.077 5p15.3
    NME5 137450.861 5q31.2
    NOP16 175810.940 5q35.2
    NR2F1 92919.043 5q14
    NR3C1 142657.496 5q31-q32
    NREP 111065.000 5q22.1
    NRG2 139226.364 5q23-q33
    NSUN2 6599.352 5p15.32
    OCLN 68788.590 5q13.1
    OSMR 38845.960 5p13.2
    OTP 76924.537 5q14.1
    OXCT1 41730.167 5p13
    P4HA2 131528.304 5q31
    PAM 102201.527 5q
    PAPD7 6714.718 5p15
    PART1 59819.923 5q12.1
    PCDH1 141242.217 5q31.3
    PCDHA@ 140165.876 5q31
    PCDHB@ 140430.979 5q31
    PCDHG@ 140710.252 5q31
    PCDHGA11 140800.537 5q31
    PCDHGA5 140743.898 5q31
    PCDHGB6 140787.770 5q31
    PCDHGC3 140855.569 5q31
    PCSK1 95726.040 5q15-q21
    PDE4D 58264.866 5q12
    PDE8B 76506.706 5q14.1
    PDLIM4 131593.351 5q31.1
    PDLIM7 176910.395 5q35.3
    PDZD2 31799.031 5p14.1
    PGGT1B 114546.527 5q23.1
    PITX1 134363.424 5q31.1
    PJA2 108670.410 5q22.1
    PLCXD3 41307.048 5p13.1
    PLEKHG4B 140.373 5p15.33
    PLK2 57749.810 5q12.1-q13.2
    POLK 74807.657 5q13
    POU4F3 145718.587 5q32
    PPAP2A 54720.670 5q11
    PPARGC1B 149109.815 5q33.1
    PPP2CA 133532.148 5q31.1
    PPP2R2B 145969.067 5q32
    PRDM9 23507.724 5p14.2
    PRKAA1 40759.481 5p13.1
    PROP1 177419.236 5q35.3
    PSD2 139175.406 5q31.3
    PTGER4 40680.032 5p13.1
    PURA 139493.708 5q31
    RAB24 176728.191 5q35.3
    RAB3C 57878.939 5q13
    RAB9BP1 104435.175 5q21.2
    RAD1 34905.366 5p13
    RAD17 68665.887 5q13
    RAD50 131892.616 5q23-q31
    RANBP17 170288.896 5q34
    RAPGEF6 130759.614 5q31.1
    RASA1 86564.070 5q13
    RASGEF1C 179527.795 5q35.3
    RASGRF2 80256.508 5q13
    RBM22 150070.352 5q33.1
    RGMB 98104.999 5q21.1
    RGS14 176784.844 5q35.3
    RHOBTB3 95066.850 5q15
    RICTOR 38938.023 5p13.1
    RIOK2 96502.450 5q14
    RNF130 179382.067 5q35.3
    RNF14 141346.402 5q23.3-q31.1
    RNF180 63461.671 5q12.3
    RNF44 175953.700 5q35.3
    RNU2-1 110820.971 17q12
    ROPN1L 10441.974 5p15
    RXFP3 33936.491 5p15.1-p14
    SAP30L 153825.517 5q33.2
    SCAMP1 77656.327 5q14.1
    SCGB3A1 180017.105 5q35-qter
    SCGB3A2 147258.274 5q32
    SDHA 218.356 5p15
    SEMA5A 9035.138 5p15.2
    SEPT8 132086.509 5q31
    SKP1 133492.082 5q31
    SKP1P1 133493.426 7q11.21
    SKP2 36152.145 5p13
    SLC12A2 127419.483 5q23.3
    SLC12A7 1050.489 5p15
    SLC1A3 36606.457 5p13
    SLC22A4 131630.145 5q23.3
    SLC22A5 131705.401 5q23.3
    SLC23A1 138702.885 5q31.2
    SLC26A2 149340.300 5q31-q34
    SLC36A1 150827.163 5q33.1
    SLC45A2 33945.972 5p13.3
    SLC6A19 1201.710 5p15
    SLC6A3 1392.905 5p15.3
    SLC9A3 473.334 5p15.3
    SLU7 159828.648 5q33.3
    SMAD5 135468.534 5q31
    SNCAIP 121647.820 5q23.2
    SNCB 176047.210 5q35
    SNX2 122110.691 5q23.2
    SPARC 151040.657 5q31-q33
    SPINK1 147204.143 5q32
    SPINK5 147443.535 5q31-q32
    SPOCK1 136310.987 5q31.2
    SPRY4 141689.992 5q31.3
    SPRY4-IT1 141697.199 5q31.3
    SQSTM1 179233.388 5q35
    SRA1 139929.652 5q31
    SRD5A1 6633.500 5p15.31
    SSBP2 80713.179 5q14.1
    ST8SIA4 100142.639 5q21
    STARD4 110834.022 5q22
    STC2 172741.726 5q35.2
    STK10 171469.074 5q35.1
    SUB1 32585.605 5p13.3
    TAF7 140698.057 5q31
    TAF9 68660.570 5q11.2-q13.1
    TBC1D9B 179289.071 5q35.3
    TCF7 133451.298 5q31
    TENM2 166711.843 5q35
    TERT 1253.287 5p15.33
    THBS4 79331.170 5q13
    TIMD4 156346.293 5q33.3
    TMEM173 138855.113 5q31.2
    TNFAIP8 118604.387 5q23.1
    TNIP1 150409.504 5q32-q33.1
    TNPO1 72112.418 5q13.1
    TPPP 659.977 5p15.33
    TRIM23 64885.507 5q12.3
    TRIM36 114506.799 5q22
    TRIP13 892.969 5p15
    TSLP 110407.390 5q22.1
    UBE2B 133706.867 5q31.1
    UBE2D2 138940.751 5q31.3
    UBE2QL1 6448.736 5p15.31
    UIMC1 176332.006 5q35.2
    UNC5A 176237.560 5q35.3
    VTRNA2-1 135416.187 5q31.1
    WDR55 140044.384 5q31.3
    WNT8A 137419.774 5q31
    XRCC4 82373.317 5q14.2
    YIPF5 143537.723 5q31.3
    YTHDC2 112849.391 5q22.3
    ZDHHC11 795.720 5p15.2
    ZNF131 43121.642 5p12
    ZNF300 150273.954 5q33.1
    ZNF366 71739.234 5q13.2|5q13.2
    ZRSR1 112227.309 5q22.2

    GeneCards  

    Contributor(s)

    WrittenJul 2004Philippe Dessen, Sakari Knuutila, Jean-Loup Huret
    UpdatedAug 2014Philippe Dessen, Jean-Loup Huret

    Citation

    This paper should be referenced as such :
    Dessen P, Knuutila S, Huret JL . Chromosome . Atlas Genet Cytogenet Oncol Haematol. Jul 2004 .
    URL : http://AtlasGeneticsOncology.org/Indexbychrom/idxa_5.html
    Dessen P, Huret JL . Chromosome . Atlas Genet Cytogenet Oncol Haematol. Aug 2014 .
    URL : http://AtlasGeneticsOncology.org/Indexbychrom/idxa_5.html
    © Atlas of Genetics and Cytogenetics in Oncology and Haematology
    indexed on : Thu Aug 21 17:58:15 CEST 2014


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