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Chromosome 18

Chromosome 18 : G-banding, diagram and R-banding - Claude Léonard, Jean-Loup Huret
Chromosome 18 diagrams ISCN 2009 - Courtesy Nicole Chia

Leukaemia     

t(1;18)(q25;q23)
t(1;18)(q10;q10)
t(2;18)(p11;q21)
t(3;18)(q26;q11)
t(3;18)(q27;p11) (NHL; BCL6 and EIF4A2; rare)
der(9;18)(p10;q10)
t(11;18)(q21;q21)
t(14;18)(q32;q21) (IgH/BCL2)
t(14;18)(q32;q21)(IgH/MALT1)
+18 or trisomy 18 in lymphoproliferative disorders
t(18;21)(q21;q22)
t(18;22)(q21;q11)

Solid Tumors     

t(X;18)(p11.2;q11.2)
(X;18)(p11;q11)

Cancer prone diseases     

All Genes by Location (Kb)
Chromosome 18 by location

Losses / Amplicons     

BONE/SOFT TISSUE

External links     

  • Chromosome 18 - HUGO Chromosomes
  • Chromosome 18 - GoldenPath - Santa Cruz
  • Chromosome 18 - Ensembl Project
  • Chromosome 18 - Map View - NCBI
  • Chromosome 18 - GDB (Genome Data Base)
  • Chromosome 18 - OMIM Gene map
  • Chromosome 18 - Genomic Variants
  • Chromosome 18 - HAPMAP Project
  • Chromosome 18 - Genome Channel - ORNL
  • Chromosome 18 - LaunchPad HGMIS
  • Chromosome 18 - Human Protein Atlas
  • Chromosome 18 - SpliceNest
  • Chromosome 18 - Array BAC clone - Roswell Park Cancer Institute
  • Chromosome 18 Human BAC Resource (NCBI)
  • Chromosome 18 FISH-mapped BACs (CCAP)
  • Genetic Maps (CHLC)
  • YACs mapped by FISH (Bari)
  • PCP (Partial Chromosome Paints) (Bari)
  • Mouse homology - OMIM - NCBI
  • Chromosome 18 Cancer GeneWeb
  • Chromosome 18 GeneCards (Weizmann)
  • Human Proteomics Initiative (Expasy)

    • Genes

    Annotated genes
    Ordered by Name Ordered by Location
     Kb pter-qter
    EPB41L3 5382.388 18p11.32
    RBBP8 18767.293 18q11.2
    SS18 21850.215 18q11.2
    DSG2 27332.025 18q12.1
    SMAD2 43613.464 18q21.1
    MAPK4 46340.482 18q12-q21
    SMAD4 46810.581 18q21.1
    MBD2 49934.573 18q21
    MALT1 54489.598 18q21
    PHLPP1 58533.714 18q21.33
    BCL2 58941.559 18q21.33|18q21.3
    SERPINB5 59295.124 18q21.3
    Other genes
    possibly implicated
    in cancer
    Ordered by Name Ordered by Location
     Kb pter-qter
    USP14 148.483 18p11.32
    CETN1 570.369 18p11.32
    TYMS 647.604 18p11.32
    YES1 711.592 18p11.31-p11.21
    ADCYAP1 894.944 18p11
    METTL4 2527.524 18p11.32
    NDC80 2561.510 18p11.32
    MYOM1 3056.805 18p11.31
    MYL12A 3237.528 18p11.31
    TGIF1 3440.172 18p11.3
    LAMA1 6931.886 18p11.31-p11.23
    PTPRM 7557.314 18p11.2
    RAB12 8599.443 18p11.22
    RALBP1 9465.530 18p11.3
    PPP4R1 9536.792 18p11.22
    RAB31 9698.228 18p11.3
    APCDD1 10444.625 18p11.22
    GNAL 11741.562 18p11.22-p11.21
    IMPA2 11971.455 18p11.2
    CIDEA 12244.318 18p11.21|18
    PSMG2 12693.064 18p11.21
    PTPN2 12783.247 18p11.3-p11.2
    MC2R 13872.043 18p11.2
    ANKRD30B 14738.239 18p11.21
    ROCK1 16783.701 18q11.1
    GREB1L 17076.201 18q11.1-q11.2
    ESCO1 17363.260 18q11.2
    MIB1 17575.543 18q11.2
    GATA6 18003.414 18q11.1-q11.2
    CTAGE1 18247.562 18p11.2
    CABLES1 18969.725 18q11.2
    RIOK3 19286.785 18q11.2
    C18orf8 19337.460 18q11.2
    LAMA3 19706.982 18q11.2
    HRH4 20294.591 18q11.2
    ZNF521 20895.886 18q11.2
    AQP4 22686.005 18q11.2-q12.1
    CDH2 23784.928 18q11.2
    DSC3 26824.050 18q12.1
    DSC2 26899.940 18q12.1
    DSC1 26963.214 18q12.2|18q12.1
    DSG1 27152.050 18q12.1
    DSG3 27281.730 18q12.1-q12.2
    TTR 27425.728 18q12.1
    RNF125 27852.443 18q12.1
    RNF138 27925.835 18q12.1
    MEP1B 28023.985 18q12.2-q12.3
    MAPRE2 30810.890 18q12.1-q12.2
    ZNF271 31124.297 18q12
    ZNF24 31166.176 18q12
    INO80C 31302.289 18q12.2
    GALNT1 31488.531 18q12.1
    SLC39A6 31944.961 18q12.2
    FHOD3 32131.700 18q12
    PIK3C3 37789.197 18q12.3
    RIT2 38577.190 18q12.3
    SETBP1 40514.136 18q21.1
    SLC14A1 41558.090 18q11-q12
    PSTPIP2 41817.500 18q12
    PIAS2 42646.058 18q21.1
    IER3IP1 42935.411 18q12
    FUSSEL18 43011.492 18q21.1
    SMAD7 44700.221 18q21.1
    MBD1 46049.214 18q21
    ME2 46659.433 6p25-p24|18q21
    ELAC1 46748.385 18q21
    MEX3C 46954.918 18q21.2
    DCC 48120.569 18q21.3
    POLI 50049.847 18q21.1
    RAB27B 50646.838 18q21.2
    CCDC68 50719.740 18q21
    TCF4 51040.560 18q21.1
    ONECUT2 53253.915 18q21.1-q21.2
    ATP8B1 53464.657 18q21-q22|18q21.31
    NEDD4L 53865.456 18q21
    GRP 55038.380 18q21.1-q21.32
    LMAN1 55146.037 18q21.3-q22
    CCBE1 55252.127 18q21.32
    PMAIP1 55718.172 18q21.32
    MC4R 56189.544 18q22
    CDH20 57308.755 18q22-q23
    RNF152 57633.284 18q21.33
    PIGN 57862.438 18q21.33
    TNFRSF11A 58143.528 18q22.1
    ZCCHC2 58341.638 18q21.33
    KDSR 59145.951 18q21.3
    SERPINB13 59405.514 18q21.3-q22
    SERPINB4 59455.473 18q21.3
    SERPINB3 59473.411 18q21.3
    SERPINB2 59705.919 18q21.3
    SERPINB8 59788.243 18q21.3
    CDH7 61569.137 18q22-q23
    CDH19 62322.301 18q22-q23
    CD226 65681.173 18q22.3
    SOCS6 66107.117 18q22.2
    CNDP1 70352.672 18q22.3
    TSHZ1 71051.719 18q22.3
    MBP 72819.777 18q23
    GALR1 73090.996 18q23
    SALL3 74841.263 18q23
    NFATC1 75256.760 18q23
    TXNL4A 75833.855 18q23

    GeneCards  

    Contributor(s)

    WrittenJul 2004Philippe Dessen, Sakari Knuutila, Jean-Loup Huret
    Updated Jean-Loup Huret, Philippe Dessen

    Citation

    This paper should be referenced as such :
    Dessen P, Knuutila S, Huret JL . Chromosome . Atlas Genet Cytogenet Oncol Haematol. Jul 2004 .
    URL : http://AtlasGeneticsOncology.org/Indexbychrom/idxa_.html
    Dessen P, Huret JL . Chromosome . Atlas Genet Cytogenet Oncol Haematol. .
    URL : http://AtlasGeneticsOncology.org/Indexbychrom/idxa_.html
    © Atlas of Genetics and Cytogenetics in Oncology and Haematology
    indexed on : Mon Mar 8 20:27:45 CET 2010
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