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CASE REPORTS in HAEMATOLOGY
(Paper co-edited with the European LeukemiaNet)
Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 1
 
Written2005-01Kavita S. Reddy, Kathy Richkind
Genzyme Genetics, Orange, CA. Kavita.reddy@gmail.com
Clinics
Age and sex : 57 year(s) old female patient.
Previous History : no preleukemia
Organomegaly : no hepatomegaly ; no splenomegaly ; no enlarged lymph nodes ; no central nervous system involvement
Blood
WBC : 3.8 x 109/L ; Hb : 11.4 g/dL ; platelets : 160 x 109/L;
Cyto pathology classification
Precise diagnosis : Myelodysplastic syndrome (MDS): refractory anaemia
Survival
Treatment : Maintenance therapy for MDS patient declined bone marrow transplantation (BMT)
Relapse : -
Status : Alive
Survival : 42 month(s)
Karyotype
Sample : BM ; culture time : 24/48 h, unstimulated cultures ; banding : G-banding
Results : 46,X,t(X;20)(q13;q13.3)[5]/46,XX[15]
Fig. 1. Partial karyotypes of the translocation t(X;20)(q13;q13.3) for cases 1ï4 (top to bottom). Arrows indicate the derivatives 20 and X.
Internal links
Atlas Cardt(X;20)(q13;q13)
Case ReportTranslocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 2
Case ReportTranslocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 3
Case ReportTranslocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 4
Bibliography
Characterization by chromosome painting of balanced and unbalanced X chromosome translocations in myelodysplastic syndromes.
Michaux L, Wlodarska I, Mecucci C, Hernandez JM, Van Orshoven A, Michaux JL, Van den Berghe H
Cancer genetics and cytogenetics. 1995 ; 82 (1) : 17-22.
PMID 7627929
 
Translocation (X;20)(q13.1;q13.3) as a primary chromosomal finding in two patients with myelocytic disorders.
Gray BA, Cornfield D, Bent-Williams A, Zori RT
Cancer genetics and cytogenetics. 2003 ; 141 (2) : 169-174.
PMID 12606138
 
Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders.
Reddy KS, Richkind K, Ross M, Seirra R
Cancer genetics and cytogenetics. 2005 ; 157 (1) : 70-73.
PMID 15676151
 

Citation

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On line version : http://AtlasGeneticsOncology.org/Reports/0X20ReddyID100009.html

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