CASE REPORTS in HAEMATOLOGY (Paper co-edited with the European LeukemiaNet)

Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 1

WARNING: on Feb 2008, we have been aware that this case had simultaneously been published in another Journal (namely Cancer Genet Cytogenet), although double reports are objectionable.

Kavita S. Reddy, Kathy Richkind

Clinics

Age and sex :	57 year(s) old female patient.
Previous History :	no preleukemia
Organomegaly :	no hepatomegaly ; no splenomegaly ; no enlarged lymph nodes ; no central nervous system involvement

Blood

WBC : 3.8 x 109/l; Hb : 11.4 g/dl; platelets : 160 x 109/l;

Cyto pathology classification

Precise diagnosis : Myelodysplastic syndrome (MDS): refractory anaemia

Survival

Treatment : Maintenance therapy for MDS patient declined bone marrow transplantation (BMT)

Relapse : -

Status : Alive

Survival : 42 month(s)

Karyotype

Sample : BM ; culture time : 24/48 h, unstimulated cultures ; banding : G-banding

Results : 46,X,t(X;20)(q13;q13.3)[5]/46,XX[15]

Fig. 1. Partial karyotypes of the translocation t(X;20)(q13;q13.3) for cases 1•4 (top to bottom). Arrows indicate the derivatives 20 and X.

Internal links

Atlas Card	t(X;20)(q13;q13)
Case Report	Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 2
Case Report	Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 3
Case Report	Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 4

Bibliography

Characterization by chromosome painting of balanced and unbalanced X chromosome translocations in myelodysplastic syndromes.

Michaux L, Wlodarska I, Mecucci C, Hernandez JM, Van Orshoven A, Michaux JL, Van den Berghe H

Cancer genetics and cytogenetics. 1995 ; 82 (1) : 17-22.

PMID 7627929

Translocation (X;20)(q13.1;q13.3) as a primary chromosomal finding in two patients with myelocytic disorders.

Gray BA, Cornfield D, Bent-Williams A, Zori RT

Cancer genetics and cytogenetics. 2003 ; 141 (2) : 169-174.

PMID 12606138

Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders.

Reddy KS, Richkind K, Ross M, Seirra R

Cancer genetics and cytogenetics. 2005 ; 157 (1) : 70-73.

PMID 15676151

Contributor(s)

Written

01-2005

Kavita S. Reddy, Kathy Richkind

Citation

This paper should be referenced as such :

Reddy KS, Richkind KE . Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 1. Atlas Genet Cytogenet Oncol Haematol. January 2005 . URL : http://AtlasGeneticsOncology.org/Reports/0X20ReddyID100009.html

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indexed on : Mon Aug 11 21:22:54 2008

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