Atlas of Genetics and Cytogenetics in Oncology and Haematology
| CASE REPORTS in
HAEMATOLOGY (Paper co-edited with the European LeukemiaNet) |
| Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 2 |
| WARNING: on Feb 2008, we have been aware that this case had simultaneously been published in another Journal (namely Cancer Genet Cytogenet), although double reports are objectionable. |
| Kavita S Reddy, Kathy Richkind |
| Clinics |
| Age and sex : | 61 year(s) old female patient. |
| Organomegaly : | no hepatomegaly ; no splenomegaly ; no enlarged lymph nodes ; no central nervous system involvement |
| Blood |
| WBC : 3.05 x 109/l; Hb : 8.1 g/dl; platelets : 62 x 109/l; |
| Cyto pathology classification |
| Precise diagnosis : Myelofibrosis -> acute leukemia |
| Survival |
| Treatment : Induction treatment: topotecan and cytarabine |
| Relapse : - |
| Status : Alive |
| Survival : 55 month(s) |
| Karyotype |
| Sample : PB ; culture time : 24/48 h, unstimulated cultures ; banding : G-banding |
| Results : 46,X,t(X;20)(q13;q13.3),der(1;7)(q10;p10)[20]/46,XX[1] |
 |
| Fig. 1. Partial karyotypes of the translocation t(X;20)(q13;q13.3) for cases 1•4 (top to bottom). Arrows indicate the derivatives 20 and X. |
| Internal links |
| Bibliography |
| Characterization by chromosome painting of balanced and unbalanced X chromosome translocations in myelodysplastic syndromes. |
| Michaux L, Wlodarska I, Mecucci C, Hernandez JM, Van Orshoven A, Michaux JL, Van den Berghe H. |
| Cancer Genet Cytogenet 1995; 82: 17•22. |
| PMID 7627929 |
| Translocation (X;20)(q13.1;q13.3) as a primary chromosomal finding in two patients with myelocytic disorders. |
| Gray BA, Cornfield D, Bent-Williams A, Zori RT. |
| Cancer Genet Cytogenet 2003; 141: 169•174. |
| PMID 12606138 |
| Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders. |
| Reddy KS, Richkind K, Ross M, Seirra R. |
| Cancer Genet Cytogenet 2005; 151: 70-73. |
| PMID 15676151 |
| Contributor(s) |
| Written | 01-2005 | Kavita S Reddy, Kathy Richkind |
| Citation |
| This paper should be referenced as such : |
| Reddy KS, Richkind KE . Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 2. Atlas Genet Cytogenet Oncol Haematol. January 2005 . URL : http://AtlasGeneticsOncology.org/Reports/0X20ReddyID100010.html |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Thu Apr 17 14:15:25 2008 |
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