| Written | 08-2018 | Jean-Loup Huret, Philippe Dessen |
| Identity |
| Atlas_Id | 100002 |
| Phylum | Lung, Heart, Skin, Other: Skin:: |
| WHO/OMS Classification | Lung, Heart, Skin, Other |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Skin: Melanocytic neoplasm, special type |
| Genes involved and Proteins |
| Gene Name | LMNA |
| Location | 1q22 |
| Gene Name | NTRK1 |
| Location | 1q23.1 |
| Bibliography |
| Kinase fusions are frequent in Spitz tumours and spitzoid melanomas |
| Wiesner T, He J, Yelensky R, Esteve-Puig R, Botton T, Yeh I, Lipson D, Otto G, Brennan K, Murali R, Garrido M, Miller VA, Ross JS, Berger MF, Sparatta A, Palmedo G, Cerroni L, Busam KJ, Kutzner H, Cronin MT, Stephens PJ, Bastian BC |
| Nat Commun 2014;5:3116 |
| PMID 24445538 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| del(1)(q22q23) LMNA/NTRK1 | |
| External links |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Thu Feb 14 17:42:58 CET 2019 |
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