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del(6)(q22q22) GOPC/ROS1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 105696
Phylum Nervous system: Central Nervous system::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Nervous system: Central Nervous system:Astrocytoma, grade III-IV/Glioblastoma

Genes involved and Proteins

Gene NameGOPC
Location 6q22.1

Gene NameROS1
Location 3q11.1

Bibliography

Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21)
Charest A, Lane K, McMahon K, Park J, Preisinger E, Conroy H, Housman D
Genes Chromosomes Cancer 2003 May;37(1):58-71
PMID 12661006
 
Novel GOPC(FIG)-ROS1 fusion in a pediatric high-grade glioma survivor
Kiehna EN, Arnush MR, Tamrazi B, Cotter JA, Hawes D, Robison NJ, Fong CY, Estrine DB, Han JH, Biegel JA
J Neurosurg Pediatr 2017 Jul;20(1):51-55
PMID 28387643
 


Translocations implicated (Data extracted from papers in the Atlas)

 del(6)(q22q22) GOPC/ROS1

External links

Mitelman database del(6)(q22q22) [CaseList]    del(6)(q22q22) [Transloc - MCList] GOPC/ROS1 [Fusion - MCList]
COSMIC[ GOPC ]   [ ROS1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databasedel(6)(q22q22) GOPC/ROS1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Feb 23 20:27:28 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.