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del(10)(q25q25) VTI1A/TCF7L2

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 109759
Phylum Digestive organs: Colon-Rectum::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Digestive organs: Colon-Rectum:Adenocarcinoma

Genes involved and Proteins

Gene NameVTI1A
Location 10q25.2

Gene NameTCF7L2
Location 10q25.2-q25.3

Bibliography

Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion
Bass AJ, Lawrence MS, Brace LE, Ramos AH, Drier Y, Cibulskis K, Sougnez C, Voet D, Saksena G, Sivachenko A, Jing R, Parkin M, Pugh T, Verhaak RG, Stransky N, Boutin AT, Barretina J, Solit DB, Vakiani E, Shao W, Mishina Y, Warmuth M, Jimenez J, Chiang DY, Signoretti S, Kaelin WG Jr, Spardy N, Hahn WC, Hoshida Y, Ogino S, DePinho RA, Chin L, Garraway LA, Fuchs CS, Baselga J, Tabernero J, Gabriel S, Lander ES, Getz G, Meyerson M
Nat Genet 2011 Sep 4;43(10):964-968
PMID 21892161
 
Comprehensive molecular characterization of human colon and rectal cancer
Cancer Genome Atlas Network
Nature 2012 Jul 18;487(7407):330-7
PMID 22810696
 


Translocations implicated (Data extracted from papers in the Atlas)

 del(10)(q25q25) VTI1A/TCF7L2

External links

Mitelman database del(10)(q25q25) [CaseList]    del(10)(q25q25) [Transloc - MCList] VTI1A/TCF7L2 [Fusion - MCList]
COSMIC[ VTI1A ]   [ TCF7L2 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databasedel(10)(q25q25) VTI1A/TCF7L2
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Feb 23 20:27:30 CET 2018


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jlhuret@AtlasGeneticsOncology.org.