dup(3)(p25p25) SRGAP3/RAF1

0000-00-00   Jean-Loup Huret , Philippe Dessen 

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

SRGAP3

Location

3p25.3

Gene name

RAF1

Location

3p25.2

Bibliography

Pubmed IDLast YearTitleAuthors
193635222009Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma.Jones DT et al
193738552009Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas.Forshew T et al

Citation

Jean-Loup Huret ; Philippe Dessen

dup(3)(p25p25) SRGAP3/RAF1

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/100049/dup(3)(p25p25)-srgap3-raf1