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dup(3)(p25p25) SRGAP3/RAF1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 101047
Phylum Nervous system: Central Nervous system::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Nervous system: Central Nervous system:Astrocytoma, pilocytic/juvenile

Genes involved and Proteins

Gene NameSRGAP3
Location 3p25.3

Gene NameRAF1
Location 3p25.2

Bibliography

Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma
Jones DT, Kocialkowski S, Liu L, Pearson DM, Ichimura K, Collins VP
Oncogene 2009 May 21;28(20):2119-23
PMID 19363522
 
Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas
Forshew T, Tatevossian RG, Lawson AR, Ma J, Neale G, Ogunkolade BW, Jones TA, Aarum J, Dalton J, Bailey S, Chaplin T, Carter RL, Gajjar A, Broniscer A, Young BD, Ellison DW, Sheer D
J Pathol 2009 Jun;218(2):172-81
PMID 19373855
 


Translocations implicated (Data extracted from papers in the Atlas)

 dup(3)(p25p25) SRGAP3/RAF1

External links

Mitelman database dup(3)(p25p25) [CaseList]     dup(3)(p25p25) [Transloc - MCList]   SRGAP3/RAF1 Fusion - MCList]
COSMIC[ SRGAP3 ]   [ RAF1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databasedup(3)(p25p25) SRGAP3/RAF1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Jun 22 17:47:40 CEST 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.