Atlas of Genetics and Cytogenetics in Oncology and Haematology

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inv(1)(q23q31) TPR/NTRK1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 6620
Phylum ::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease :Neuro-Endocrine/Endocrine System: Thyroid: Papillary carcinoma: inv(1)(q23q31) TPR/NTRK1

Genes involved and Proteins

Gene NameTPR
Location 3p26.1

Gene NameNTRK1
Location 1q23.1


Characterization of the NTRK1 genomic region involved in chromosomal rearrangements generating TRK oncogenes
Greco A, Mariani C, Miranda C, Pagliardini S, Pierotti MA
Genomics 1993 Nov;18(2):397-400
PMID 8288244
Chromosome 1 rearrangements involving the genes TPR and NTRK1 produce structurally different thyroid-specific TRK oncogenes
Greco A, Miranda C, Pagliardini S, Fusetti L, Bongarzone I, Pierotti MA
Genes Chromosomes Cancer 1997 Jun;19(2):112-23
PMID 9172002

Translocations implicated (Data extracted from papers in the Atlas)

 inv(1)(q23q31) TPR/NTRK1

External links

Mitelman database inv(1)(q23q31) [CaseList]     inv(1)(q23q31) [Transloc - MCList]   TPR/NTRK1 Fusion - MCList]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaseinv(1)(q23q31) TPR/NTRK1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Fri Jun 22 17:47:45 CEST 2018

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