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inv(2)(p23p23) CAD/ALK

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 109694
Phylum Digestive organs: Colon-Rectum::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Digestive organs: Colon-Rectum:Adenocarcinoma

Genes involved and Proteins

Gene NameCAD
Location 2q34

Gene NameALK
Location 2p23.2-p23.1

Bibliography

Novel CAD-ALK gene rearrangement is drugable by entrectinib in colorectal cancer
Amatu A, Somaschini A, Cerea G, Bosotti R, Valtorta E, Buonandi P, Marrapese G, Veronese S, Luo D, Hornby Z, Multani P, Murphy D, Shoemaker R, Lauricella C, Giannetta L, Maiolani M, Vanzulli A, Ardini E, Galvani A, Isacchi A, Sartore-Bianchi A, Siena S
Br J Cancer 2015 Dec 22;113(12):1730-4
PMID 26633560
 


Translocations implicated (Data extracted from papers in the Atlas)

 inv(2)(p23p23) CAD/ALK

External links

Mitelman database inv(2)(p23p23) [CaseList]    inv(2)(p23p23) [Transloc - MCList] CAD/ALK [Fusion - MCList]
COSMIC[ CAD ]   [ ALK ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaseinv(2)(p23p23) CAD/ALK
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Tue Feb 6 17:45:34 CET 2018


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jlhuret@AtlasGeneticsOncology.org.