Atlas of Genetics and Cytogenetics in Oncology and Haematology

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inv(6)(q13q24) COL12A1/GRM1

Written08-2018Jean-Loup Huret, Philippe Dessen

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Atlas_Id 100075
Phylum Bones: Bones::
WHO/OMS Classification Bones
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Bones: Chondromyxoid fibroma

Genes involved and Proteins

Gene NameCOL12A1
Location 6q13

Gene NameGRM1
Location 6q24.3


GRM1 is upregulated through gene fusion and promoter swapping in chondromyxoid fibroma
Nord KH, Lilljebjörn H, Vezzi F, Nilsson J, Magnusson L, Tayebwa J, de Jong D, Bovée JV, Hogendoorn PC, Szuhai K
Nat Genet 2014 May;46(5):474-7
PMID 24658000

Translocations implicated (Data extracted from papers in the Atlas)

 inv(6)(q13q24) COL12A1/GRM1

External links

Mitelman database inv(6)(q13q24) [CaseList]     inv(6)(q13q24) [Transloc - MCList]   COL12A1/GRM1 Fusion - MCList]
COSMIC[ COL12A1 ]   [ GRM1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaseinv(6)(q13q24) COL12A1/GRM1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Thu Feb 14 17:43:17 CET 2019

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