| Written | 08-2018 | Jean-Loup Huret, Philippe Dessen |
| Identity |
| Atlas_Id | 100078 |
| Phylum | Nervous system: Central Nervous system:: |
| WHO/OMS Classification | Nervous system |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Central Nervous system: Primitive neuroectodermal tumor/Medulloblastoma |
| Genes involved and Proteins |
| Gene Name | PVT1 |
| Location | 8q24.21 |
| Gene Name | ZC3H3 |
| Location | 8q24.3 |
| Bibliography |
| The whole-genome landscape of medulloblastoma subtypes |
| Northcott PA, Buchhalter I, Morrissy AS, Hovestadt V, Weischenfeldt J, Ehrenberger T, Gröbner S, Segura-Wang M, Zichner T, Rudneva VA, Warnatz HJ, Sidiropoulos N, Phillips AH, Schumacher S, Kleinheinz K, Waszak SM, Erkek S, Jones DTW, Worst BC, Kool M, Zapatka M, Jäger N, Chavez L, Hutter B, Bieg M, Paramasivam N, Heinold M, Gu Z, Ishaque N, Jäger-Schmidt C, Imbusch CD, Jugold A, Hübschmann D, Risch T, Amstislavskiy V, Gonzalez FGR, Weber UD, Wolf S, Robinson GW, Zhou X, Wu G, Finkelstein D, Liu Y, Cavalli FMG, Luu B, Ramaswamy V, Wu X, Koster J, Ryzhova M, Cho YJ, Pomeroy SL, Herold-Mende C, Schuhmann M, Ebinger M, Liau LM, Mora J, McLendon RE, Jabado N, Kumabe T, Chuah E, Ma Y, Moore RA, Mungall AJ, Mungall KL, Thiessen N, Tse K, Wong T, Jones SJM, Witt O, Milde T, Von Deimling A, Capper D, Korshunov A, Yaspo ML, Kriwacki R, Gajjar A, Zhang J, Beroukhim R, Fraenkel E, Korbel JO, Brors B, Schlesner M, Eils R, Marra MA, Pfister SM, Taylor MD, Lichter P |
| Nature 2017 Jul 19;547(7663):311-317 |
| PMID 28726821 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| inv(8)(q24q24) PVT1/ZC3H3 | |
| External links |
| Mitelman database | inv(8)(q24q24) [Fusion] inv(8)(q24q24) [Cytogenetics Case] |
| COSMIC | [ PVT1 ] [ ZC3H3 ] |
| Disease database | inv(8)(q24q24) PVT1/ZC3H3 |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Jul 13 11:02:48 CEST 2020 |
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