inv(8)(q24q24) PVT1/ZC3H3

Identity

Atlas_Id	100078
Phylum	Nervous system: Central Nervous system::
WHO/OMS Classification	Nervous system
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Central Nervous system: Primitive neuroectodermal tumor/Medulloblastoma

Genes involved and Proteins

Gene Name	PVT1
Location	8q24.21

Gene Name	ZC3H3
Location	8q24.3

Bibliography

The whole-genome landscape of medulloblastoma subtypes

Northcott PA, Buchhalter I, Morrissy AS, Hovestadt V, Weischenfeldt J, Ehrenberger T, Gröbner S, Segura-Wang M, Zichner T, Rudneva VA, Warnatz HJ, Sidiropoulos N, Phillips AH, Schumacher S, Kleinheinz K, Waszak SM, Erkek S, Jones DTW, Worst BC, Kool M, Zapatka M, Jäger N, Chavez L, Hutter B, Bieg M, Paramasivam N, Heinold M, Gu Z, Ishaque N, Jäger-Schmidt C, Imbusch CD, Jugold A, Hübschmann D, Risch T, Amstislavskiy V, Gonzalez FGR, Weber UD, Wolf S, Robinson GW, Zhou X, Wu G, Finkelstein D, Liu Y, Cavalli FMG, Luu B, Ramaswamy V, Wu X, Koster J, Ryzhova M, Cho YJ, Pomeroy SL, Herold-Mende C, Schuhmann M, Ebinger M, Liau LM, Mora J, McLendon RE, Jabado N, Kumabe T, Chuah E, Ma Y, Moore RA, Mungall AJ, Mungall KL, Thiessen N, Tse K, Wong T, Jones SJM, Witt O, Milde T, Von Deimling A, Capper D, Korshunov A, Yaspo ML, Kriwacki R, Gajjar A, Zhang J, Beroukhim R, Fraenkel E, Korbel JO, Brors B, Schlesner M, Eils R, Marra MA, Pfister SM, Taylor MD, Lichter P

Nature 2017 Jul 19;547(7663):311-317

PMID 28726821

Translocations implicated (Data extracted from papers in the Atlas)

	inv(8)(q24q24) PVT1/ZC3H3

External links

Mitelman database	inv(8)(q24q24) [CaseList]     inv(8)(q24q24) [Transloc - MCList]   PVT1/ZC3H3 Fusion - MCList]
COSMIC	[ PVT1 ]   [ ZC3H3 ]
arrayMap	arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease database	inv(8)(q24q24) PVT1/ZC3H3

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Feb 14 17:43:18 CET 2019

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