| Written | 08-2018 | Jean-Loup Huret, Philippe Dessen |
| Identity |
| Atlas_Id | 103934 |
| Phylum | Digestive organs: Colon-Rectum:: |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Colon-Rectum: Adenocarcinoma |
| Genes involved and Proteins |
| Gene Name | LMNA |
| Location | 1q22 |
| Gene Name | NTRK1 |
| Location | 1q23.1 |
| Bibliography |
| Sensitivity to Entrectinib Associated With a Novel LMNA-NTRK1 Gene Fusion in Metastatic Colorectal Cancer |
| Sartore-Bianchi A, Ardini E, Bosotti R, Amatu A, Valtorta E, Somaschini A, Raddrizzani L, Palmeri L, Banfi P, Bonazzina E, Misale S, Marrapese G, Leone A, Alzani R, Luo D, Hornby Z, Lim J, Veronese S, Vanzulli A, Bardelli A, Martignoni M, Davite C, Galvani A, Isacchi A, Siena S |
| J Natl Cancer Inst 2015 Nov 12;108(1) |
| PMID 26563355 |
| NTRK1 fusions for the therapeutic intervention of Korean patients with colon cancer |
| Park DY, Choi C, Shin E, Lee JH, Kwon CH, Jo HJ, Kim HR, Kim HS, Oh N, Lee JS, Park OK, Park E, Park J, Shin JY, Kim JI, Seo JS, Park HD, Park J |
| Oncotarget 2016 Feb 16;7(7):8399-412 |
| PMID 26716414 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(1;1)(q22;q23) LMNA/NTRK1 | |
| External links |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Fri Oct 5 17:09:29 CEST 2018 |
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