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t(1;1)(q22;q23) LMNA/NTRK1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 108411
Phylum Soft Tissues::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Soft Tissues:Fibrosarcoma

Genes involved and Proteins

Gene NameLMNA
Location 1q22

Gene NameNTRK1
Location 1q23.1

Bibliography

Evaluation of a Congenital Infantile Fibrosarcoma by Comprehensive Genomic Profiling Reveals an LMNA-NTRK1 Gene Fusion Responsive to Crizotinib
Wong V, Pavlick D, Brennan T, Yelensky R, Crawford J, Ross JS, Miller VA, Malicki D, Stephens PJ, Ali SM, Ahn H
J Natl Cancer Inst 2015 Nov 12;108(1)
PMID 26563356
 
Identification of NTRK fusions in pediatric mesenchymal tumors
Pavlick D, Schrock AB, Malicki D, Stephens PJ, Kuo DJ, Ahn H, Turpin B, Allen JM, Rosenzweig M, Badizadegan K, Ross JS, Miller VA, Wong V, Ali SM
Pediatr Blood Cancer 2017 Aug;64(8)
PMID 28097808
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(1;1)(q22;q23) LMNA/NTRK1

External links

Mitelman database t(1;1)(q22;q23) [CaseList]     t(1;1)(q22;q23) [Transloc - MCList]   LMNA/NTRK1 Fusion - MCList]
COSMIC[ LMNA ]   [ NTRK1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(1;1)(q22;q23) LMNA/NTRK1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Jun 22 17:49:34 CEST 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.