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t(1;6)(p35;p21) PUM1/TRERF1

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 104466
Phylum Female organs: Breast::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Breast: Adenocarcinoma

Genes involved and Proteins

Gene NamePUM1
Location 1p35.2

Gene NameTRERF1
Location 6p21.1

Bibliography

A novel bioinformatics pipeline for identification and characterization of fusion transcripts in breast cancer and normal cell lines
Asmann YW, Hossain A, Necela BM, Middha S, Kalari KR, Sun Z, Chai HS, Williamson DW, Radisky D, Schroth GP, Kocher JP, Perez EA, Thompson EA
Nucleic Acids Res 2011 Aug;39(15):e100
PMID 21622959
 
Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer
Robinson DR, Kalyana-Sundaram S, Wu YM, Shankar S, Cao X, Ateeq B, Asangani IA, Iyer M, Maher CA, Grasso CS, Lonigro RJ, Quist M, Siddiqui J, Mehra R, Jing X, Giordano TJ, Sabel MS, Kleer CG, Palanisamy N, Natrajan R, Lambros MB, Reis-Filho JS, Kumar-Sinha C, Chinnaiyan AM
Nat Med 2011 Nov 20;17(12):1646-51
PMID 22101766
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(1;6)(p35;p21) PUM1/TRERF1

External links

Mitelman database t(1;6)(p35;p21) [CaseList]     t(1;6)(p35;p21) [Transloc - MCList]   PUM1/TRERF1 Fusion - MCList]
COSMIC[ PUM1 ]   [ TRERF1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(1;6)(p35;p21) PUM1/TRERF1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Oct 5 17:10:53 CEST 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.