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t(1;8)(q44;q24) AKT3/PVT1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 105034
Phylum Lung, Heart, Skin, Other: Lung::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Lung, Heart, Skin, Other: Lung:Undifferentiated carcinoma, small cell

Genes involved and Proteins

Gene NameAKT3
Location 1q43

Gene NamePVT1
Location 8q24.21

Bibliography

Genomic organization and evolution of double minutes/homogeneously staining regions with MYC amplification in human cancer
L'Abbate A, Macchia G, D'Addabbo P, Lonoce A, Tolomeo D, Trombetta D, Kok K, Bartenhagen C, Whelan CW, Palumbo O, Severgnini M, Cifola I, Dugas M, Carella M, De Bellis G, Rocchi M, Carbone L, Storlazzi CT
Nucleic Acids Res 2014 Aug;42(14):9131-45
PMID 25034695
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(1;8)(q44;q24) AKT3/PVT1

External links

Mitelman database t(1;8)(q44;q24) [CaseList]     t(1;8)(q44;q24) [Transloc - MCList]   AKT3/PVT1 Fusion - MCList]
COSMIC[ AKT3 ]   [ PVT1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(1;8)(q44;q24) AKT3/PVT1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Jun 22 17:50:56 CEST 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.