t(1;10)(p13;q11) TRIM33/RET

0000-00-00   Jean-Loup Huret , Philippe Dessen 

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

TRIM33

Location

1p13.2

Gene name

RET

Location

10q11.21

Highly cited references

Pubmed IDYearTitleCitations
235332642013Response to Cabozantinib in patients with RET fusion-positive lung adenocarcinomas.186
331351962021Oncocytic intraductal carcinoma of salivary glands: a distinct variant with TRIM33-RET fusions and BRAF V600E mutations.8
317621462020Next-generation sequencing in salivary gland carcinoma: Targetable alterations lead to a therapeutic advantage-Multicenter experience.2
349856832022Frankly Invasive Carcinoma Ex-intraductal Carcinoma: Expanding on an Emerging and Perplexing Concept in Salivary Gland Tumor Pathology.1

Bibliography

Pubmed IDLast YearTitleAuthors
104390471999The transcription coactivator HTIF1 and a related protein are fused to the RET receptor tyrosine kinase in childhood papillary thyroid carcinomas.Klugbauer S et al
107417392000Pattern of radiation-induced RET and NTRK1 rearrangements in 191 post-chernobyl papillary thyroid carcinomas: biological, phenotypic, and clinical implications.Rabes HM et al

Citation

Jean-Loup Huret ; Philippe Dessen

t(1;10)(p13;q11) TRIM33/RET

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/104091/t(1;10)(p13;q11)-trim33-ret