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t(1;14)(p22;q32) IGH/BCL10

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 108669
Phylum -::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease -:Extranodal marginal zone B-cell lymphoma

Genes involved and Proteins

Gene NameIGH
Location 14q32.33

Gene NameBCL10
Location 1p22.3

Bibliography

Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32)
Zhang Q, Siebert R, Yan M, Hinzmann B, Cui X, Xue L, Rakestraw KM, Naeve CW, Beckmann G, Weisenburger DD, Sanger WG, Nowotny H, Vesely M, Callet-Bauchu E, Salles G, Dixit VM, Rosenthal A, Schlegelberger B, Morris SW
Nat Genet 1999 May;22(1):63-8
PMID 10319863
 
Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types
Willis TG, Jadayel DM, Du MQ, Peng H, Perry AR, Abdul-Rauf M, Price H, Karran L, Majekodunmi O, Wlodarska I, Pan L, Crook T, Hamoudi R, Isaacson PG, Dyer MJ
Cell 1999 Jan 8;96(1):35-45
PMID 9989495
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(1;14)(p22;q32) IGH/BCL10

External links

Mitelman database t(1;14)(p22;q32) [CaseList]     t(1;14)(p22;q32) [Transloc - MCList]   IGH/BCL10 Fusion - MCList]
COSMIC[ IGH ]   [ BCL10 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(1;14)(p22;q32) IGH/BCL10
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Jun 22 17:51:20 CEST 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.