t(1;16)(p36;p12) PDPN/PRKCB

Identity

Atlas_Id	104210
Phylum	Soft Tissues: Soft Tissues::
WHO/OMS Classification	Soft Tissues
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Soft Tissues: Benign fibrous histiocytoma

Genes involved and Proteins

Gene Name	PDPN
Location	1p36.21

Gene Name	PRKCB
Location	16p12.2

Bibliography

Fusions involving protein kinase C and membrane-associated proteins in benign fibrous histiocytoma

Płaszczyca A, Nilsson J, Magnusson L, Brosjö O, Larsson O, Vult von Steyern F, Domanski HA, Lilljebjörn H, Fioretos T, Tayebwa J, Mandahl N, Nord KH, Mertens F

Int J Biochem Cell Biol 2014 Aug;53:475-81

PMID 24721208

Gene fusion detection in formalin-fixed paraffin-embedded benign fibrous histiocytomas using fluorescence in situ hybridization and RNA sequencing

Walther C, Hofvander J, Nilsson J, Magnusson L, Domanski HA, Gisselsson D, Tayebwa J, Doyle LA, Fletcher CD, Mertens F

Lab Invest 2015 Sep;95(9):1071-6

PMID 26121314

Translocations implicated (Data extracted from papers in the Atlas)

	t(1;16)(p36;p12) PDPN/PRKCB

External links

Mitelman database	t(1;16)(p36;p12) [CaseList]     t(1;16)(p36;p12) [Transloc - MCList]   PDPN/PRKCB Fusion - MCList]
COSMIC	[ PDPN ]   [ PRKCB ]
arrayMap	arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease database	t(1;16)(p36;p12) PDPN/PRKCB

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Wed Nov 28 16:31:42 CET 2018

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