Written | 08-2018 | Jean-Loup Huret, Philippe Dessen |
Identity |
Atlas_Id | 104210 |
Phylum | Soft Tissues: Soft Tissues:: |
WHO/OMS Classification | Soft Tissues |
Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
Clinics and Pathology |
Disease | Soft Tissues: Benign fibrous histiocytoma |
Genes involved and Proteins |
Gene Name | PDPN |
Location | 1p36.21 |
Gene Name | PRKCB |
Location | 16p12.2 |
Bibliography |
Fusions involving protein kinase C and membrane-associated proteins in benign fibrous histiocytoma |
Płaszczyca A, Nilsson J, Magnusson L, Brosjö O, Larsson O, Vult von Steyern F, Domanski HA, Lilljebjörn H, Fioretos T, Tayebwa J, Mandahl N, Nord KH, Mertens F |
Int J Biochem Cell Biol 2014 Aug;53:475-81 |
PMID 24721208 |
Gene fusion detection in formalin-fixed paraffin-embedded benign fibrous histiocytomas using fluorescence in situ hybridization and RNA sequencing |
Walther C, Hofvander J, Nilsson J, Magnusson L, Domanski HA, Gisselsson D, Tayebwa J, Doyle LA, Fletcher CD, Mertens F |
Lab Invest 2015 Sep;95(9):1071-6 |
PMID 26121314 |
Translocations implicated (Data extracted from papers in the Atlas) |
t(1;16)(p36;p12) PDPN/PRKCB | |
External links |
REVIEW articles | automatic search in PubMed |
Last year articles | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Thu Feb 14 17:47:06 CET 2019 |
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