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t(2;2)(p14;p22) PPP3R1/TTC27

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 105152
Phylum Female organs: Breast::
WHO/OMS Classification Female organs
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Breast: Adenocarcinoma

Genes involved and Proteins

Gene NamePPP3R1
Location 2p14

Gene NameTTC27
Location 2p22.3

Bibliography

BreakTrans: uncovering the genomic architecture of gene fusions
Chen K, Navin NE, Wang Y, Schmidt HK, Wallis JW, Niu B, Fan X, Zhao H, McLellan MD, Hoadley KA, Mardis ER, Ley TJ, Perou CM, Wilson RK, Ding L
Genome Biol 2013 Aug 23;14(8):R87
PMID 23972288
 
The landscape and therapeutic relevance of cancer-associated transcript fusions
Yoshihara K, Wang Q, Torres-Garcia W, Zheng S, Vegesna R, Kim H, Verhaak RG
Oncogene 2015 Sep 10;34(37):4845-54
PMID 25500544
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(2;2)(p14;p22) PPP3R1/TTC27

External links

Mitelman database t(2;2)(p14;p22) [CaseList]     t(2;2)(p14;p22) [Transloc - MCList]   PPP3R1/TTC27 Fusion - MCList]
COSMIC[ PPP3R1 ]   [ TTC27 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(2;2)(p14;p22) PPP3R1/TTC27
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 7 17:52:21 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.