t(2;2)(p16;p23) PPP1R21/ALK

Identity

Atlas_Id	105162
Phylum	Digestive organs: Colon-Rectum::
WHO/OMS Classification	Digestive organs
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Colon-Rectum: Adenocarcinoma

Genes involved and Proteins

Gene Name	PPP1R21
Location	2p16.3

Gene Name	ALK
Location	2p23.2

Bibliography

Oncogenic ALK Fusion in Rare and Aggressive Subtype of Colorectal Adenocarcinoma as a Potential Therapeutic Target

Yakirevich E, Resnick MB, Mangray S, Wheeler M, Jackson CL, Lombardo KA, Lee J, Kim KM, Gill AJ, Wang K, Gowen K, Sun J, Miller VA, Stephens PJ, Ali SM, Ross JS, Safran H

Clin Cancer Res 2016 Aug 1;22(15):3831-40

PMID 26933125

Translocations implicated (Data extracted from papers in the Atlas)

	t(2;2)(p16;p23) PPP1R21/ALK

External links

Mitelman database	t(2;2)(p16;p23) [CaseList]     t(2;2)(p16;p23) [Transloc - MCList]   PPP1R21/ALK Fusion - MCList]
COSMIC	[ PPP1R21 ]   [ ALK ]
arrayMap	arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease database	t(2;2)(p16;p23) PPP1R21/ALK

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Wed Nov 28 16:32:37 CET 2018

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