| Written | 08-2018 | Jean-Loup Huret, Philippe Dessen |
| Identity |
| Atlas_Id | 105162 |
| Phylum | Digestive organs: Colon-Rectum:: |
| WHO/OMS Classification | Digestive organs |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Colon-Rectum: Adenocarcinoma |
| Genes involved and Proteins |
| Gene Name | PPP1R21 |
| Location | 2p16.3 |
| Gene Name | ALK |
| Location | 2p23.2 |
| Bibliography |
| Oncogenic ALK Fusion in Rare and Aggressive Subtype of Colorectal Adenocarcinoma as a Potential Therapeutic Target |
| Yakirevich E, Resnick MB, Mangray S, Wheeler M, Jackson CL, Lombardo KA, Lee J, Kim KM, Gill AJ, Wang K, Gowen K, Sun J, Miller VA, Stephens PJ, Ali SM, Ross JS, Safran H |
| Clin Cancer Res 2016 Aug 1;22(15):3831-40 |
| PMID 26933125 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(2;2)(p16;p23) PPP1R21/ALK | |
| External links |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Jul 8 15:36:39 CEST 2019 |
For comments and suggestions or contributions, please contact us