Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(2;2)(p22;p23) BIRC6/ALK

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Atlas_Id 105185
Phylum Lung, Heart, Skin, Other: Lung::
WHO/OMS Classification Lung, Heart, Skin, Other
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Lung: Adenocarcinoma

Genes involved and Proteins

Gene NameBIRC6
Location 2p22.3

Gene NameALK
Location 2p23.2


BIRC6-ALK, a Novel Fusion Gene in ALK Break-Apart FISH-Negative Lung Adenocarcinoma, Responds to Crizotinib
Shan L, Jiang P, Xu F, Zhang W, Guo L, Wu J, Zeng Y, Jiao Y, Ying J
J Thorac Oncol 2015 Jun;10(6):e37-9
PMID 26001147

Translocations implicated (Data extracted from papers in the Atlas)

 t(2;2)(p22;p23) BIRC6/ALK

External links

Mitelman database t(2;2)(p22;p23) [CaseList]     t(2;2)(p22;p23) [Transloc - MCList]   BIRC6/ALK Fusion - MCList]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(2;2)(p22;p23) BIRC6/ALK
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Mon Dec 14 18:35:14 CET 2020

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