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MAPRE3/ALK (2p23)

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 105203
Phylum Digestive organs: Colon-Rectum::
WHO/OMS Classification Digestive organs
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Colon-Rectum: Adenocarcinoma

Genes involved and Proteins

Gene NameMAPRE3
Location 2p23.3

Gene NameALK
Location 2p23.2

Bibliography

Oncogenic ALK Fusion in Rare and Aggressive Subtype of Colorectal Adenocarcinoma as a Potential Therapeutic Target
Yakirevich E, Resnick MB, Mangray S, Wheeler M, Jackson CL, Lombardo KA, Lee J, Kim KM, Gill AJ, Wang K, Gowen K, Sun J, Miller VA, Stephens PJ, Ali SM, Ross JS, Safran H
Clin Cancer Res 2016 Aug 1;22(15):3831-40
PMID 26933125
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(2;2)(p23;p23) MAPRE3/ALK

External links

Mitelman database t(2;2)(p23;p23) [CaseList]     t(2;2)(p23;p23) [Transloc - MCList]   MAPRE3/ALK Fusion - MCList]
COSMIC[ MAPRE3 ]   [ ALK ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaseMAPRE3/ALK (2p23)
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 7 17:52:37 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.