Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(2;2)(q22;q35) FN1/ACVR2A

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Atlas_Id 105288
Phylum Bones: Bones::
WHO/OMS Classification Bones
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Bones: Chondrosarcoma, NOS

Disease Bones: Osteochondroma

Genes involved and Proteins

Gene NameFN1
Location 2q35

Gene NameACVR2A
Location 2q22.3


Unique mutation portraits and frequent COL2A1 gene alteration in chondrosarcoma
Totoki Y, Yoshida A, Hosoda F, Nakamura H, Hama N, Ogura K, Yoshida A, Fujiwara T, Arai Y, Toguchida J, Tsuda H, Miyano S, Kawai A, Shibata T
Genome Res 2014 Sep;24(9):1411-20
PMID 25024164

Translocations implicated (Data extracted from papers in the Atlas)

 t(2;2)(q22;q35) FN1/ACVR2A

External links

Mitelman database t(2;2)(q22;q35) [CaseList]     t(2;2)(q22;q35) [Transloc - MCList]   FN1/ACVR2A Fusion - MCList]
COSMIC[ FN1 ]   [ ACVR2A ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(2;2)(q22;q35) FN1/ACVR2A
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Mon Sep 21 11:27:58 CEST 2020

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