Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

t(2;4)(q36;q31) PAX3/MAML3

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 111386
Phylum Head and Neck: Nose-Nasopharynx::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Head and Neck: Nose-Nasopharynx:Mesenchymal tumor, special type

Genes involved and Proteins

Gene NamePAX3
Location 2q36.1

Gene NameMAML3
Location 4q31.1

Bibliography

Recurrent PAX3-MAML3 fusion in biphenotypic sinonasal sarcoma
Wang X, Bledsoe KL, Graham RP, Asmann YW, Viswanatha DS, Lewis JE, Lewis JT, Chou MM, Yaszemski MJ, Jen J, Westendorf JJ, Oliveira AM
Nat Genet 2014 Jul;46(7):666-8
PMID 24859338
 
Novel PAX3-NCOA1 Fusions in Biphenotypic Sinonasal Sarcoma With Focal Rhabdomyoblastic Differentiation
Huang SC, Ghossein RA, Bishop JA, Zhang L, Chen TC, Huang HY, Antonescu CR
Am J Surg Pathol 2016 Jan;40(1):51-9
PMID 26371783
 
Fusion gene profile of biphenotypic sinonasal sarcoma: an analysis of 44 cases
Fritchie KJ, Jin L, Wang X, Graham RP, Torbenson MS, Lewis JE, Rivera M, Garcia JJ, Schembri-Wismayer DJ, Westendorf JJ, Chou MM, Dong J, Oliveira AM
Histopathology 2016 Dec;69(6):930-936
PMID 27454570
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(2;4)(q36;q31) PAX3/MAML3

External links

Mitelman database t(2;4)(q36;q31) [CaseList]    t(2;4)(q36;q31) [Transloc - MCList] PAX3/MAML3 [Fusion - MCList]
COSMIC[ PAX3 ]   [ MAML3 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(2;4)(q36;q31) PAX3/MAML3
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Feb 6 17:52:07 CET 2018


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.