Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

t(2;5)(p23;q35) SQSTM1/ALK

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 105459
Phylum Lung, Heart, Skin, Other: Skin::
WHO/OMS Classification Lung, Heart, Skin, Other
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Skin: Benign fibrous histiocytoma

Genes involved and Proteins

Gene NameSQSTM1
Location 5q35.3

Gene NameALK
Location 2p23.2

Bibliography

Epithelioid cell histiocytoma of the skin with clonal ALK gene rearrangement resulting in VCL-ALK and SQSTM1-ALK gene fusions
Jedrych J, Nikiforova M, Kennedy TF, Ho J
Br J Dermatol 2015;172(5):1427-9
PMID 25413595
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(2;5)(p23;q35) SQSTM1/ALK

External links

Mitelman database t(2;5)(p23;q35) [CaseList]     t(2;5)(p23;q35) [Transloc - MCList]   SQSTM1/ALK Fusion - MCList]
COSMIC[ SQSTM1 ]   [ ALK ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(2;5)(p23;q35) SQSTM1/ALK
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 28 16:33:59 CET 2018


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.