t(2;5)(p23;q35) SQSTM1/ALK

Identity

Atlas_Id	105459
Phylum	Lung, Heart, Skin, Other: Skin::
WHO/OMS Classification	Lung, Heart, Skin, Other
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Skin: Benign fibrous histiocytoma

Genes involved and Proteins

Gene Name	SQSTM1
Location	5q35.3

Gene Name	ALK
Location	2p23.2

Bibliography

Epithelioid cell histiocytoma of the skin with clonal ALK gene rearrangement resulting in VCL-ALK and SQSTM1-ALK gene fusions

Jedrych J, Nikiforova M, Kennedy TF, Ho J

Br J Dermatol 2015;172(5):1427-9

PMID 25413595

Translocations implicated (Data extracted from papers in the Atlas)

	t(2;5)(p23;q35) SQSTM1/ALK

External links

Mitelman database	t(2;5)(p23;q35) [CaseList]     t(2;5)(p23;q35) [Transloc - MCList]   SQSTM1/ALK Fusion - MCList]
COSMIC	[ SQSTM1 ]   [ ALK ]
arrayMap	arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease database	t(2;5)(p23;q35) SQSTM1/ALK

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Feb 14 17:49:00 CET 2019

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