| Written | 08-2018 | Jean-Loup Huret, Philippe Dessen |
| Identity |
| Atlas_Id | 105459 |
| Phylum | Lung, Heart, Skin, Other: Skin:: |
| WHO/OMS Classification | Lung, Heart, Skin, Other |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Skin: Benign fibrous histiocytoma |
| Genes involved and Proteins |
| Gene Name | SQSTM1 |
| Location | 5q35.3 |
| Gene Name | ALK |
| Location | 2p23.2 |
| Bibliography |
| Epithelioid cell histiocytoma of the skin with clonal ALK gene rearrangement resulting in VCL-ALK and SQSTM1-ALK gene fusions |
| Jedrych J, Nikiforova M, Kennedy TF, Ho J |
| Br J Dermatol 2015;172(5):1427-9 |
| PMID 25413595 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(2;5)(p23;q35) SQSTM1/ALK | |
| External links |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Wed Nov 28 16:33:59 CET 2018 |
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