Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(2;5)(p23;q35) SQSTM1/ALK

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Atlas_Id 105459
Phylum Lung, Heart, Skin, Other: Skin::
WHO/OMS Classification Lung, Heart, Skin, Other
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Skin: Benign fibrous histiocytoma

Genes involved and Proteins

Gene NameSQSTM1
Location 5q35.3

Gene NameALK
Location 2p23.2


Epithelioid cell histiocytoma of the skin with clonal ALK gene rearrangement resulting in VCL-ALK and SQSTM1-ALK gene fusions
Jedrych J, Nikiforova M, Kennedy TF, Ho J
Br J Dermatol 2015;172(5):1427-9
PMID 25413595

Translocations implicated (Data extracted from papers in the Atlas)

 t(2;5)(p23;q35) SQSTM1/ALK

External links

Mitelman database t(2;5)(p23;q35) [CaseList]     t(2;5)(p23;q35) [Transloc - MCList]   SQSTM1/ALK Fusion - MCList]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(2;5)(p23;q35) SQSTM1/ALK
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Mon Dec 14 18:36:08 CET 2020

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