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t(2;6)(q11;p21) AFF3/PHF1

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 105483
Phylum Soft Tissues: Soft Tissues::
WHO/OMS Classification Soft Tissues
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Soft Tissues: Myxofibrosarcoma

Genes involved and Proteins

Gene NameAFF3
Location 2q11.2

Gene NamePHF1
Location 6p21.32

Bibliography

RNA sequencing of sarcomas with simple karyotypes: identification and enrichment of fusion transcripts
Hofvander J, Tayebwa J, Nilsson J, Magnusson L, Brosjö O, Larsson O, von Steyern FV, Domanski HA, Mandahl N, Mertens F
Lab Invest 2015 Jun;95(6):603-9
PMID 25867764
 

Translocations implicated (Data extracted from papers in the Atlas)

 t(2;6)(q11;p21) AFF3/PHF1

External links

Mitelman database t(2;6)(q11;p21) [CaseList]     t(2;6)(q11;p21) [Transloc - MCList]   AFF3/PHF1 Fusion - MCList]
COSMIC[ AFF3 ]   [ PHF1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(2;6)(q11;p21) AFF3/PHF1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 28 16:34:06 CET 2018

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jlhuret@AtlasGeneticsOncology.org.