Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(2;7)(p23;q11) HIP1/ALK

(Note : for Links provided by Atlas : click)


Atlas_Id 105499
Phylum Lung, Heart, Skin, Other: Lung::
WHO/OMS Classification Lung, Heart, Skin, Other
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Lung: Adenocarcinoma

Genes involved and Proteins

Gene NameHIP1
Location 7q11.23

Gene NameALK
Location 2p23.2


HIP1-ALK, a novel ALK fusion variant that responds to crizotinib
Fang DD, Zhang B, Gu Q, Lira M, Xu Q, Sun H, Qian M, Sheng W, Ozeck M, Wang Z, Zhang C, Chen X, Chen KX, Li J, Chen SH, Christensen J, Mao M, Chan CC
J Thorac Oncol 2014 Mar;9(3):285-94
PMID 24496003
HIP1-ALK, a novel fusion protein identified in lung adenocarcinoma
Hong M, Kim RN, Song JY, Choi SJ, Oh E, Lira ME, Mao M, Takeuchi K, Han J, Kim J, Choi YL
J Thorac Oncol 2014 Mar;9(3):419-22
PMID 24518094

Translocations implicated (Data extracted from papers in the Atlas)

 t(2;7)(p23;q11) HIP1/ALK

External links

Mitelman database t(2;7)(p23;q11) [CaseList]     t(2;7)(p23;q11) [Transloc - MCList]   HIP1/ALK Fusion - MCList]
COSMIC[ HIP1 ]   [ ALK ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(2;7)(p23;q11) HIP1/ALK
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Dec 14 18:36:16 CET 2020

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