t(2;11)(p23;q22) DNMT3A/TRPC6

Identity

Atlas_Id	104983
Phylum	Urinary system: Kidney::
WHO/OMS Classification	Urinary system
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Kidney: Adenocarcinoma

Genes involved and Proteins

Gene Name	DNMT3A
Location	2p23.3

Gene Name	TRPC6
Location	11q22.1

Bibliography

Integrated molecular analysis of clear-cell renal cell carcinoma

Sato Y, Yoshizato T, Shiraishi Y, Maekawa S, Okuno Y, Kamura T, Shimamura T, Sato-Otsubo A, Nagae G, Suzuki H, Nagata Y, Yoshida K, Kon A, Suzuki Y, Chiba K, Tanaka H, Niida A, Fujimoto A, Tsunoda T, Morikawa T, Maeda D, Kume H, Sugano S, Fukayama M, Aburatani H, Sanada M, Miyano S, Homma Y, Ogawa S

Nat Genet 2013 Aug;45(8):860-7

PMID 23797736

Translocations implicated (Data extracted from papers in the Atlas)

	t(2;11)(p23;q22) DNMT3A/TRPC6

External links

Mitelman database	t(2;11)(p23;q22) [CaseList]     t(2;11)(p23;q22) [Transloc - MCList]   DNMT3A/TRPC6 Fusion - MCList]
COSMIC	[ DNMT3A ]   [ TRPC6 ]
arrayMap	arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease database	t(2;11)(p23;q22) DNMT3A/TRPC6

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Wed Nov 28 16:34:32 CET 2018

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