Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(2;15)(p21;q25) EML4/NTRK3

(Note : for Links provided by Atlas : click)


Atlas_Id 105039
Phylum Soft Tissues: Soft Tissues::
WHO/OMS Classification Soft Tissues
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Soft Tissues: Soft tissue tumor, special type

Genes involved and Proteins

Gene NameEML4
Location 2p21

Gene NameNTRK3
Location 15q25.3


Recurrent BRAF Gene Fusions in a Subset of Pediatric Spindle Cell Sarcomas: Expanding the Genetic Spectrum of Tumors With Overlapping Features With Infantile Fibrosarcoma
Kao YC, Fletcher CDM, Alaggio R, Wexler L, Zhang L, Sung YS, Orhan D, Chang WC, Swanson D, Dickson BC, Antonescu CR
Am J Surg Pathol 2018 Jan;42(1):28-38
PMID 28877062

Translocations implicated (Data extracted from papers in the Atlas)

 t(2;15)(p21;q25) EML4/NTRK3

External links

Mitelman database t(2;15)(p21;q25) [CaseList]     t(2;15)(p21;q25) [Transloc - MCList]   EML4/NTRK3 Fusion - MCList]
COSMIC[ EML4 ]   [ NTRK3 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(2;15)(p21;q25) EML4/NTRK3
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Mon Dec 14 18:36:41 CET 2020

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