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t(3;3)(p21;p21) PBRM1/CYB561D2

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 112124
Phylum -::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease -:Mesothelioma

Genes involved and Proteins

Gene NamePBRM1
Location 3p21.1

Gene NameCYB561D2
Location 3p21.31


Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations
Bueno R, Stawiski EW, Goldstein LD, Durinck S, De Rienzo A, Modrusan Z, Gnad F, Nguyen TT, Jaiswal BS, Chirieac LR, Sciaranghella D, Dao N, Gustafson CE, Munir KJ, Hackney JA, Chaudhuri A, Gupta R, Guillory J, Toy K, Ha C, Chen YJ, Stinson J, Chaudhuri S, Zhang N, Wu TD, Sugarbaker DJ, de Sauvage FJ, Richards WG, Seshagiri S
Nat Genet 2016 Apr;48(4):407-16
PMID 26928227

Translocations implicated (Data extracted from papers in the Atlas)

 t(3;3)(p21;p21) PBRM1/CYB561D2

External links

Mitelman database t(3;3)(p21;p21) [CaseList]    t(3;3)(p21;p21) [Transloc - MCList] PBRM1/CYB561D2 [Fusion - MCList]
COSMIC[ PBRM1 ]   [ CYB561D2 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(3;3)(p21;p21) PBRM1/CYB561D2
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Fri Feb 23 20:34:07 CET 2018

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