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t(3;6)(q12;q22) TFG/ROS1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 113115
Phylum Soft Tissues::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Soft Tissues:Inflammatory myofibroblastic tumor/myofibroblastic sarcoma

Genes involved and Proteins

Gene NameTFG

Gene NameROS1
Location 3q11.1

Bibliography

Inflammatory myofibroblastic tumors harbor multiple potentially actionable kinase fusions
Lovly CM, Gupta A, Lipson D, Otto G, Brennan T, Chung CT, Borinstein SC, Ross JS, Stephens PJ, Miller VA, Coffin CM
Cancer Discov 2014 Aug;4(8):889-95
PMID 24875859
 
Molecular characterization of inflammatory myofibroblastic tumors with frequent ALK and ROS1 gene fusions and rare novel RET rearrangement
Antonescu CR, Suurmeijer AJ, Zhang L, Sung YS, Jungbluth AA, Travis WD, Al-Ahmadie H, Fletcher CD, Alaggio R
Am J Surg Pathol 2015 Jul;39(7):957-67
PMID 25723109
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(3;6)(q12;q22) TFG/ROS1

External links

Mitelman database t(3;6)(q12;q22) [CaseList]    t(3;6)(q12;q22) [Transloc - MCList] TFG/ROS1 [Fusion - MCList]
COSMIC[ TFG ]   [ ROS1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(3;6)(q12;q22) TFG/ROS1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Fri Feb 23 20:35:18 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.