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t(3;20)(p21;q12) SDC4/SPCS1

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 105706
Phylum Nervous system: Central Nervous system::
WHO/OMS Classification Nervous system
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Central Nervous system: Astrocytoma, grade III-IV/Glioblastoma

Genes involved and Proteins

Gene NameSDC4
Location 20q13.12

Gene NameSPCS1
Location 3p21.1

Bibliography

The integrated landscape of driver genomic alterations in glioblastoma
Frattini V, Trifonov V, Chan JM, Castano A, Lia M, Abate F, Keir ST, Ji AX, Zoppoli P, Niola F, Danussi C, Dolgalev I, Porrati P, Pellegatta S, Heguy A, Gupta G, Pisapia DJ, Canoll P, Bruce JN, McLendon RE, Yan H, Aldape K, Finocchiaro G, Mikkelsen T, Privé GG, Bigner DD, Lasorella A, Rabadan R, Iavarone A
Nat Genet 2013 Oct;45(10):1141-9
PMID 23917401
 
The landscape and therapeutic relevance of cancer-associated transcript fusions
Yoshihara K, Wang Q, Torres-Garcia W, Zheng S, Vegesna R, Kim H, Verhaak RG
Oncogene 2015 Sep 10;34(37):4845-54
PMID 25500544
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(3;20)(p21;q12) SDC4/SPCS1

External links

Mitelman database t(3;20)(p21;q12) [CaseList]     t(3;20)(p21;q12) [Transloc - MCList]   SDC4/SPCS1 Fusion - MCList]
COSMIC[ SDC4 ]   [ SPCS1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(3;20)(p21;q12) SDC4/SPCS1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 28 16:38:20 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.