| Written | 2018-01 | Jean-Loup Huret, Philippe Dessen |
| Identity |
| Atlas_Id | 6776 |
| Phylum | Lung:: |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to How to contribute |
| Clinics and Pathology |
| Disease | Lung:Lung, Heart, Skin, Other: Lung: Non-small cell carcinoma: Adenocarcinoma: t(4;6)(p15;q22) SLC34A2/ROS1 |
| Genes involved and Proteins |
| Gene Name | SLC34A2 |
| Location | 4p15.2 |
| Gene Name | ROS1 |
| Location | 3q11.1 |
| Bibliography |
| Analysis of receptor tyrosine kinase ROS1-positive tumors in non-small cell lung cancer: identification of a FIG-ROS1 fusion |
| Rimkunas VM, Crosby KE, Li D, Hu Y, Kelly ME, Gu TL, Mack JS, Silver MR, Zhou X, Haack H |
| Clin Cancer Res 2012 Aug 15;18(16):4449-57 |
| PMID 22661537 |
| Identifying and targeting ROS1 gene fusions in non-small cell lung cancer |
| Davies KD, Le AT, Theodoro MF, Skokan MC, Aisner DL, Berge EM, Terracciano LM, Cappuzzo F, Incarbone M, Roncalli M, Alloisio M, Santoro A, Camidge DR, Varella-Garcia M, Doebele RC |
| Clin Cancer Res 2012 Sep 1;18(17):4570-9 |
| PMID 22919003 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(4;6)(p15;q22) SLC34A2/ROS1 | |
| External links |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon May 14 14:01:37 CEST 2018 |
For comments and suggestions or contributions, please contact us