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t(4;6)(p15;q22) SLC34A2/ROS1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 6776
Phylum Lung::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Lung:Lung, Heart, Skin, Other: Lung: Non-small cell carcinoma: Adenocarcinoma: t(4;6)(p15;q22) SLC34A2/ROS1

Genes involved and Proteins

Gene NameSLC34A2
Location 4p15.2

Gene NameROS1
Location 3q11.1


Analysis of receptor tyrosine kinase ROS1-positive tumors in non-small cell lung cancer: identification of a FIG-ROS1 fusion
Rimkunas VM, Crosby KE, Li D, Hu Y, Kelly ME, Gu TL, Mack JS, Silver MR, Zhou X, Haack H
Clin Cancer Res 2012 Aug 15;18(16):4449-57
PMID 22661537
Identifying and targeting ROS1 gene fusions in non-small cell lung cancer
Davies KD, Le AT, Theodoro MF, Skokan MC, Aisner DL, Berge EM, Terracciano LM, Cappuzzo F, Incarbone M, Roncalli M, Alloisio M, Santoro A, Camidge DR, Varella-Garcia M, Doebele RC
Clin Cancer Res 2012 Sep 1;18(17):4570-9
PMID 22919003

Translocations implicated (Data extracted from papers in the Atlas)

 t(4;6)(p15;q22) SLC34A2/ROS1

External links

Mitelman database t(4;6)(p15;q22) [CaseList]    t(4;6)(p15;q22) [Transloc - MCList] SLC34A2/ROS1 [Fusion - MCList]
COSMIC[ SLC34A2 ]   [ ROS1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(4;6)(p15;q22) SLC34A2/ROS1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Fri Mar 9 17:55:48 CET 2018

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