| Written | 08-2018 | Jean-Loup Huret, Philippe Dessen |
| Identity |
| Atlas_Id | 106471 |
| Phylum | Nervous system: Central Nervous system:: |
| WHO/OMS Classification | Nervous system |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Central Nervous system: Astrocytoma, grade III-IV/Glioblastoma |
| Genes involved and Proteins |
| Gene Name | NAA15 |
| Location | 4q31.1 |
| Gene Name | LPAR1 |
| Location | 9q31.3 |
| Bibliography |
| A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival |
| Zheng S, Fu J, Vegesna R, Mao Y, Heathcock LE, Torres-Garcia W, Ezhilarasan R, Wang S, McKenna A, Chin L, Brennan CW, Yung WK, Weinstein JN, Aldape KD, Sulman EP, Chen K, Koul D, Verhaak RG |
| Genes Dev 2013 Jul 1;27(13):1462-72 |
| PMID 23796897 |
| Exploration of the gene fusion landscape of glioblastoma using transcriptome sequencing and copy number data |
| Shah N, Lankerovich M, Lee H, Yoon JG, Schroeder B, Foltz G |
| BMC Genomics 2013 Nov 22;14:818 |
| PMID 24261984 |
| The landscape and therapeutic relevance of cancer-associated transcript fusions |
| Yoshihara K, Wang Q, Torres-Garcia W, Zheng S, Vegesna R, Kim H, Verhaak RG |
| Oncogene 2015 Sep 10;34(37):4845-54 |
| PMID 25500544 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(4;9)(q31;q31) NAA15/LPAR1 | |
| External links |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Thu Feb 14 17:53:21 CET 2019 |
For comments and suggestions or contributions, please contact us