MAN2A1/FER (5q21)

0000-00-00   Jean-Loup Huret , Philippe Dessen 

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

MAN2A1

Location

5q21.3

Gene name

FER

Location

5q21.3

Highly cited references

Pubmed IDYearTitleCitations
284594522017Targeting genomic rearrangements in tumor cells through Cas9-mediated insertion of a suicide gene.38
252389352014Novel fusion transcripts associate with progressive prostate cancer.25
282454302017MAN2A1-FER Fusion Gene Is Expressed by Human Liver and Other Tumor Types and Has Oncogenic Activity in Mice.20
311649572019Detection of fusion transcripts in the serum samples of patients with hepatocellular carcinoma.9
344175382021Detection of fusion gene transcripts in the blood samples of prostate cancer patients.1

Bibliography

Pubmed IDLast YearTitleAuthors
282454302017MAN2A1-FER Fusion Gene Is Expressed by Human Liver and Other Tumor Types and Has Oncogenic Activity in Mice.Chen ZH et al

Citation

Jean-Loup Huret ; Philippe Dessen

MAN2A1/FER (5q21)

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/106698/man2a1-fer-(5q21)