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t(5;6)(q33;q22) PWWP2A/ROS1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 112943
Phylum Lung, Heart, Skin, Other: Skin::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Lung, Heart, Skin, Other: Skin:Melanocytic neoplasm, special type

Genes involved and Proteins

Gene NamePWWP2A
Location 5q33.3

Gene NameROS1
Location 3q11.1


Kinase fusions are frequent in Spitz tumours and spitzoid melanomas
Wiesner T, He J, Yelensky R, Esteve-Puig R, Botton T, Yeh I, Lipson D, Otto G, Brennan K, Murali R, Garrido M, Miller VA, Ross JS, Berger MF, Sparatta A, Palmedo G, Cerroni L, Busam KJ, Kutzner H, Cronin MT, Stephens PJ, Bastian BC
Nat Commun 2014;5:3116
PMID 24445538

Translocations implicated (Data extracted from papers in the Atlas)

 t(5;6)(q33;q22) PWWP2A/ROS1

External links

Mitelman database t(5;6)(q33;q22) [CaseList]    t(5;6)(q33;q22) [Transloc - MCList] PWWP2A/ROS1 [Fusion - MCList]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(5;6)(q33;q22) PWWP2A/ROS1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Fri Feb 23 20:37:48 CET 2018

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