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t(5;8)(q33;p12) CD74/NRG1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 109997
Phylum Lung, Heart, Skin, Other: Lung::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Lung, Heart, Skin, Other: Lung:Adenocarcinoma

Genes involved and Proteins

Gene NameCD74
Location 5q33.1

Gene NameNRG1
Location 8p12


CD74-NRG1 fusions in lung adenocarcinoma
Fernandez-Cuesta L, Plenker D, Osada H, Sun R, Menon R, Leenders F, Ortiz-Cuaran S, Peifer M, Bos M, Daßler J, Malchers F, Schöttle J, Vogel W, Dahmen I, Koker M, Ullrich RT, Wright GM, Russell PA, Wainer Z, Solomon B, Brambilla E, Nagy-Mignotte H, Moro-Sibilot D, Brambilla CG, Lantuejoul S, Altmüller J, Becker C, Nürnberg P, Heuckmann JM, Stoelben E, Petersen I, Clement JH, Sänger J, Muscarella LA, la Torre A, Fazio VM, Lahortiga I, Perera T, Ogata S, Parade M, Brehmer D, Vingron M, Heukamp LC, Buettner R, Zander T, Wolf J, Perner S, Ansén S, Haas SA, Yatabe Y, Thomas RK
Cancer Discov 2014 Apr;4(4):415-22
PMID 24469108
Multidriver mutation analysis in pulmonary mucinous adenocarcinoma in Taiwan: identification of a rare CD74-NRG1 translocation case
Gow CH, Wu SG, Chang YL, Shih JY
Med Oncol 2014 Jul;31(7):34
PMID 24913807

Translocations implicated (Data extracted from papers in the Atlas)

 t(5;8)(q33;p12) CD74/NRG1

External links

Mitelman database t(5;8)(q33;p12) [CaseList]    t(5;8)(q33;p12) [Transloc - MCList] CD74/NRG1 [Fusion - MCList]
COSMIC[ CD74 ]   [ NRG1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(5;8)(q33;p12) CD74/NRG1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Fri Feb 23 20:37:56 CET 2018

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