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t(5;10)(q35;q26) FGFR2/NPM1

Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

Atlas_Id 106487
Phylum Digestive organs: Colon-Rectum::
WHO/OMS Classification Digestive organs
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Colon-Rectum: Adenocarcinoma

Genes involved and Proteins

Gene NameFGFR2
Location 10q26.13

Gene NameNPM1
Location 5q35.1

Bibliography

The FGFR Landscape in Cancer: Analysis of 4,853 Tumors by Next-Generation Sequencing
Helsten T, Elkin S, Arthur E, Tomson BN, Carter J, Kurzrock R
Clin Cancer Res 2016 Jan 1;22(1):259-67
PMID 26373574
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(5;10)(q35;q26) FGFR2/NPM1

External links

Mitelman database t(5;10)(q35;q26) [CaseList]     t(5;10)(q35;q26) [Transloc - MCList]   FGFR2/NPM1 Fusion - MCList]
COSMIC[ FGFR2 ]   [ NPM1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(5;10)(q35;q26) FGFR2/NPM1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


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indexed on : Wed Nov 28 16:40:59 CET 2018


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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.