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t(6;6)(p21;p21) SYNGAP1/HSP90AB1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)


Atlas_Id 106024
Phylum Nervous system: Central Nervous system::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Nervous system: Central Nervous system:Astrocytoma, grade III-IV/Glioblastoma

Genes involved and Proteins

Gene NameSYNGAP1
Location 6p21.32

Gene NameHSP90AB1
Location 6p21.1


A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival
Zheng S, Fu J, Vegesna R, Mao Y, Heathcock LE, Torres-Garcia W, Ezhilarasan R, Wang S, McKenna A, Chin L, Brennan CW, Yung WK, Weinstein JN, Aldape KD, Sulman EP, Chen K, Koul D, Verhaak RG
Genes Dev 2013 Jul 1;27(13):1462-72
PMID 23796897

Translocations implicated (Data extracted from papers in the Atlas)

 t(6;6)(p21;p21) SYNGAP1/HSP90AB1

External links

Mitelman database t(6;6)(p21;p21) [CaseList]    t(6;6)(p21;p21) [Transloc - MCList] SYNGAP1/HSP90AB1 [Fusion - MCList]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(6;6)(p21;p21) SYNGAP1/HSP90AB1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Fri Feb 23 20:38:32 CET 2018

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