Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(6;6)(p21;p21) UBR2/SRPK1

Written2018-01Jean-Loup Huret, Philippe Dessen

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Atlas_Id 109140
Phylum Female organs: Breast::
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

Clinics and Pathology

Disease Female organs: Breast:Adenocarcinoma

Genes involved and Proteins

Gene NameUBR2
Location 6p21.1

Gene NameSRPK1


Detection of redundant fusion transcripts as biomarkers or disease-specific therapeutic targets in breast cancer
Asmann YW, Necela BM, Kalari KR, Hossain A, Baker TR, Carr JM, Davis C, Getz JE, Hostetter G, Li X, McLaughlin SA, Radisky DC, Schroth GP, Cunliffe HE, Perez EA, Thompson EA
Cancer Res 2012 Apr 15;72(8):1921-8
PMID 22496456

Translocations implicated (Data extracted from papers in the Atlas)

 t(6;6)(p21;p21) UBR2/SRPK1

External links

Mitelman database t(6;6)(p21;p21) [CaseList]    t(6;6)(p21;p21) [Transloc - MCList] UBR2/SRPK1 [Fusion - MCList]
COSMIC[ UBR2 ]   [ SRPK1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(6;6)(p21;p21) UBR2/SRPK1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

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indexed on : Fri Feb 23 20:38:37 CET 2018

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